This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction: High Glucose Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells Are Regulated by FoxO3a
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsFOXO transcription factor regulation · Signaling Pathways in Disease · Heat shock proteins research
After this article [1] was published, concerns were raised regarding results presented in Figs 2, 6 and 7. Specifically,
The authors did not respond to editorial request for comment on these concerns.
In light of the above concerns which call into question the integrity and reliability of [1], the PLOS One Editors retract this article.
All authors either did not respond directly or could not be reached.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Peng C, Ma J, Gao X, Tian P, Li W, Zhang L. High glucose induced oxidative stress and apoptosis in cardiac microvascular endothelial cells are regulated by Fox O 3a. P Lo S One. 2013;8(11):e 79739. doi: 10.1371/journal.pone.0079739 24260294 PMC 3832590 · doi ↗ · pubmed ↗
- 2Zhang S, Zhao Y, Xu M, Yu L, Zhao Y, Chen J, et al. Fox O 3a modulates hypoxia stress induced oxidative stress and apoptosis in cardiac microvascular endothelial cells. P Lo S One. 2013;8(11):e 80342. doi: 10.1371/journal.pone.0080342 24278276 PMC 3835407 · doi ↗ · pubmed ↗
- 3Zhang S, Zhao Y, Xu M, Yu L, Zhao Y, Chen J, et al. Correction: Fox O 3a Modulates Hypoxia Stress Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells. P Lo S One. 2013;8(12). doi: 10.1371/annotation/1c 419628-f 1b 5-45de-9f 8a-43f 834309 ebb 29161729 PMC 5703077 · doi ↗ · pubmed ↗
- 4Chen C, Yao L, Cui J, Liu B. Retracted Paper - Fisetin Protects against Intracerebral Hemorrhage-Induced Neuroinflammation in Aged Mice. Cerebrovasc Dis. 2018;45(3–4):154–61. doi: 10.1159/000488117 29587289 · doi ↗ · pubmed ↗
- 5Retraction Statement: Paper by Cheng Chen, Li Yao, Jing Cui, and Bao Liu entitled “Fisetin Protects against Intracerebral Hemorrhage-Induced Neuroinflammation in Aged Mice” [Cerebrovasc Dis. 14 May 2018;45(3–4):154–161. https://doi.org/10.1159/000488117]. Cerebrovasc Dis 10 December 2024; 53(6):794. doi: 10.1159/00054044929587289 · doi ↗ · pubmed ↗
- 6Zhang Z, Zhao C, Liu B, Liang D, Qin X, Li X, et al. Inositol pyrophosphates mediate the effects of aging on bone marrow mesenchymal stem cells by inhibiting Akt signaling. Stem Cell Res Ther. 2014;5(2):33. doi: 10.1186/scrt 431 24670364 PMC 4055148 · doi ↗ · pubmed ↗