# Radioanatomy of the Silent Sinus Syndrome

**Authors:** Paula von der Lage, Adrian Dalbert, Michael Soyka

PMC · DOI: 10.1002/oto2.70212 · OTO Open · 2026-03-03

## TL;DR

This study examines radiological changes in silent sinus syndrome, showing how it affects surrounding anatomical structures and poses risks during surgery.

## Contribution

The study quantifies specific radiological changes in inferoposterior structures associated with silent sinus syndrome.

## Key findings

- The pterygopalatine fossa and tuber maxillae are significantly larger on the affected side in SSS.
- The orbital floor and sinus rear wall show stronger indentation in SSS cases.
- The affected maxillary sinus has a significantly reduced volume in SSS patients.

## Abstract

Silent sinus syndrome (SSS) arises from negative pressure in the maxillary sinus through occlusion of the ethmoidal infundibulum. Convexity of the surrounding bone towards the lumen and a hypoglobus can occur. It may endanger surrounding structures during endoscopic sinus surgery. This research identifies and quantifies radiological changes in inferoposterior anatomical structures associated with SSS.

Retrospective case series study.

Computed tomography and magnetic resonance imaging scans of 23 patients with SSS who were treated at the University Hospital of Zurich between 2013 and 2023 were evaluated.

The volume of the maxillary sinus, the orbital floor and sinus rear wall convexity, the height of the tuber maxillae, and the pterygopalatine fossa dimension were measured. The affected side was quantitatively compared with the healthy side.

The extension of the pterygopalatine fossa and the height of the tuber maxillae were significantly larger on the affected side (mean difference = 2.354 mm, 4.99 mm; P < .01 for both). A stronger indentation of the back wall (mean difference = 3.763 mm; P < .01) and the orbital floor (mean difference = 2.268 mm; P < .01) was measured in SSS. In addition, the syndrome reduces the volume of the affected maxillary sinus (mean difference = 8.885 mL; P < .01).

SSS causes a marked enlargement of the neighbouring inferoposterior anatomical spaces. Shrinking of the sinus' volume could explain this effect. These findings have direct clinical implications, as the surgeon might inadvertently enter these structures more easily in SSS.

## Linked entities

- **Diseases:** silent sinus syndrome (MONDO:0019108)

## Full-text entities

- **Diseases:** osteolysis (MESH:D010014), diplopia (MESH:D004172), maxillary sinus atelectasis (MESH:D008444), CMA (MESH:D001261), asymmetries (MESH:D005146), endonasal neoplasia (MESH:D009369), antrum syndrome (MESH:D013577), inflammatory (MESH:D007249), trauma (MESH:D014947), SSS (MESH:D012804), Nasal septal deviation (MESH:D061270), affected (MESH:D019964)
- **Chemicals:** FESS (-), gadolinium (MESH:D005682)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12955829/full.md

## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12955829/full.md

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Source: https://tomesphere.com/paper/PMC12955829