# Ocular manifestations in a cohort of patients with mpox in the Democratic Republic of the Congo 2007–2011

**Authors:** Placide Mbala-Kingebeni, Nam V. Nguyen, Jean-Claude Mwanza, Jessica Carag, Susanne Linderman, Tolulope Fashina, Eddy Kinganda, Tony Wawina-Bokalanga, Amuri Aziza, Jean-Claude Makangara-Cigolo, Emmanuel Hasivirwe Vakaniaki, Yvon Anta, Jepsy Yango, Olivier Tshiani, Jason Kindrachuk, Laurens Liesenborghs, Christophe Van Dijck, Martine Peeters, Eric Delaporte, Anne W. Rimoin, John W. Huggins, Therese Riu-Rovira, Steve M. Ahuka, James W. Martin, Ian Crozier, Steven Yeh, Jean-Jacques Muyembe

PMC · DOI: 10.1128/asmcr.00171-25 · ASM Case Reports · 2026-02-11

## TL;DR

This study reports on eye-related symptoms in patients with mpox in the Democratic Republic of the Congo, showing that nearly 8% experienced various ocular issues.

## Contribution

The study provides new insights into the range of ocular manifestations associated with Clade I mpox in a specific geographic region.

## Key findings

- Ocular manifestations were observed in 8.3% of 216 patients with mpox.
- Common symptoms included conjunctivitis, eyelid lesions, and keratitis.
- Some ocular manifestations could lead to serious vision-threatening complications.

## Abstract

This report describes the ocular manifestations in a cohort of patients with Clade I mpox evaluated in the Democratic Republic of the Congo from 2007 to 2011, as well as the clinical course of a 3-year-old patient with mpox associated with ocular disease. Among 216 patients, ocular manifestations were observed in 8.3%, including conjunctivitis, eyelid lesions, eyelid swelling, eye pain, orbital swelling, keratitis, and corneal staphyloma. These findings highlight the broad spectrum of ocular manifestations with potentially sight-threatening consequences in patients with mpox.

## Full-text entities

- **Diseases:** keratitis (MESH:D007634), Clade I mpox (MESH:D006969), corneal staphyloma (MESH:D003316), ocular disease (MESH:D005128), eye pain (MESH:D058447), orbital swelling (MESH:D009916), conjunctivitis (MESH:D003231), eyelid lesions (MESH:D005141)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12955382/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12955382/full.md

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Source: https://tomesphere.com/paper/PMC12955382