# Depression, self-efficacy, and the mediating role of self-esteem: evidence from women entrepreneurs

**Authors:** Hassan HassanAhmadi, MohammadJawad Hoseinzadeh

PMC · DOI: 10.3389/fpubh.2025.1716599 · Frontiers in Public Health · 2026-02-17

## TL;DR

This study shows that depression lowers self-esteem and self-efficacy in women entrepreneurs, and improving self-esteem can help counter these effects.

## Contribution

The study identifies self-esteem as a partial mediator between depression and self-efficacy in women entrepreneurs.

## Key findings

- Depression negatively predicts both self-esteem and self-efficacy in women entrepreneurs.
- Self-esteem significantly mediates the relationship between depression and self-efficacy (R2 = 0.49).
- Enhancing self-esteem can mitigate the negative effects of depression and improve entrepreneurial resilience.

## Abstract

This study investigates the relationship between depression and self-efficacy among women entrepreneurs in Herat, with a particular emphasis on the mediating role of self-esteem. The entrepreneurial context, while offering financial independence and personal growth, also exposes women to significant psychological stressors such as financial insecurity, patriarchal norms, and limited social support. A total of 110 entrepreneurial women aged 20–45 participated in this research through convenience sampling. Data were collected using standardized instruments: the Beck Depression Inventory-II (BDI-II), the Coopersmith Self-Esteem Inventory (SEI), and the General Self-Efficacy Scale (GSE). Analysis was performed using Partial Least Squares Structural Equation Modeling (PLS-SEM). Findings revealed that depression negatively predicted both self-esteem and self-efficacy, while self-esteem exerted a significant positive effect on self-efficacy. Mediation testing confirmed that self-esteem partially mediated the relationship between depression and self-efficacy, explaining a substantial proportion of the variance in self-efficacy (R2 = 0.49). These results highlight the dual psychological challenges faced by women entrepreneurs, where depressive symptoms reduce both perceived competence and self-worth, subsequently lowering efficacy. The study demonstrates that enhancing self-esteem is a key pathway to mitigating the detrimental effects of depression and improving entrepreneurial resilience. Practical implications include the development of interventions such as cognitive-behavioral therapy, self-esteem enhancement workshops, and peer-support initiatives tailored to entrepreneurial contexts. By addressing both depressive symptoms and self-esteem, such strategies may strengthen self-efficacy, support women's psychological well-being, and ultimately promote sustainable entrepreneurial success in developing economies.

## Linked entities

- **Diseases:** depression (MONDO:0002050)

## Full-text entities

- **Diseases:** eating disorders (MESH:D001068), Depression (MESH:D003866), anxiety (MESH:D001007), mental illness (MESH:D001523), post-traumatic stress disorder (MESH:D013313)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC12954620/full.md

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Source: https://tomesphere.com/paper/PMC12954620