# Ultra-distal bypass remains a valuable option for tibial disease with tissue loss

**Authors:** Waad Ahmed, Megan Power Foley, Seamus McHugh, Sayed Aly, Peter Naughton, Daragh Moneley, Elrasheid Kheirelseid

PMC · DOI: 10.1016/j.jvscit.2026.102157 · Journal of Vascular Surgery Cases, Innovations and Techniques · 2026-01-24

## TL;DR

Ultra-distal bypass surgery helps heal leg ulcers in patients with complex tibial disease and tissue loss, despite variable long-term success.

## Contribution

This study provides real-world outcomes of ultra-distal bypass in a specific patient population with tibial disease and tissue loss.

## Key findings

- 85% of ulcers healed at the most recent follow-up.
- Freedom from major amputation was 92% at 12 months.
- Freedom from graft failure was 68% at 12 months.

## Abstract

The pattern of distal tibial calcific disease associated with chronic kidney disease (CKD) and diabetes is challenging to revascularize. Ultra-distal bypass, on to pedal or plantar vessels, is an option for patients who have failed an endovascular approach. The goal of such ultra-distal bypasses is often to achieve wound healing rather than long-term patency. We present a retrospective observational study from an Irish tertiary vascular center.

A retrospective review of all ultra-distal bypasses since 2019 was performed. Cases were identified from theater logs. Electronic health records and formal charts were used to record demographics, comorbidities and outcomes. Statistical analysis was performed using SPSS.

Since 2019, 25 limbs in 23 patients underwent ultra-distal bypass for tissue loss, 16 to pedal vessels and 9 to plantars. All patients were male and the median age was 62.0 years (range, 43-85 years). Seventy-two percent (n = 18/25) of the cohort were diabetic, 36% had chronic kidney disease, 4 (16%) were dialysis dependent, and 5 (20%) had congestive heart failure. Median follow-up duration was 14 months (range, 0-51 months). At 12 months, freedom from graft failure was 68% (n = 17/25) and freedom from major amputation was 92% (n = 23/25). At the most recent clinic review, 85% (n = 17/20) of ulcers had healed.

Ultra-distal bypasses are a valuable tool in a vascular surgeon's arsenal for tissue loss in patients with complex tibial disease. Although the durability of bypass was variable, the majority of patients included in this study healed their ulcers and only three limbs progressed to major amputation.

## Linked entities

- **Diseases:** chronic kidney disease (MONDO:0005300), diabetes (MONDO:0005015), congestive heart failure (MONDO:0005009)

## Full-text entities

- **Diseases:** tibial disease (MESH:D020429), thrombosis (MESH:D013927), Critical (MESH:D016638), hematomas (MESH:D006406), disease (MESH:D004194), limb loss (MESH:D001259), hypertension (MESH:D006973), death (MESH:D003643), end-stage renal disease (MESH:D007676), ischemic heart disease (MESH:D017202), diabetes (MESH:D003920), calcific disease (MESH:D002114), renal failure (MESH:D051437), infection (MESH:D007239), CKD (MESH:D051436), ulcers (MESH:D014456), Wound, Ischemia, and foot Infection 3- (MESH:D014946), CLTI (MESH:D000089802), Congestive cardiac failure (MESH:D006333), renal impairment (MESH:D007674), PAD (MESH:D058729), insulin-dependent diabetes (MESH:D003922), CCF (MESH:D003025), gangrene (MESH:D005734), necrotic (MESH:D009336), diabetic nephropathy (MESH:D003928), Limb Ischemia (MESH:D007511), stage 3 (MESH:D062706), Ischaemia of the Leg-2 (MESH:C538360), tissue (MESH:D017695)
- **Chemicals:** clopidogrel (MESH:D000077144), antiplatelet (-), Aquacel (MESH:D002266), Aspirin (MESH:D001241), Iodoflex (MESH:C038634)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12954191/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12954191/full.md

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Source: https://tomesphere.com/paper/PMC12954191