# Surgical repair of peripherally inserted central catheter extravasation via a transmanubrial approach

**Authors:** Masashi Bungo, Hisashi Uemura, Akifumi Nakamura, Taichi Sakaguchi

PMC · DOI: 10.1016/j.jvscit.2026.102160 · Journal of Vascular Surgery Cases, Innovations and Techniques · 2026-01-25

## TL;DR

A 76-year-old woman with a catheter complication was successfully treated using a transmanubrial surgical approach.

## Contribution

The paper presents a novel surgical application of the transmanubrial approach for treating catheter-related mediastinal abscesses.

## Key findings

- The transmanubrial approach allowed successful catheter removal and abscess drainage in a complex case.
- The TMA preserves neck and shoulder mobility, making it suitable for older, frail patients.
- Catheter tip migration and venous perforation can lead to severe complications requiring surgical intervention.

## Abstract

The transmanubrial approach (TMA) offers great exposure for managing complex superior mediastinal pathology while preserving functional anatomy. Here, we report a case of extravascular perforation caused by peripherally inserted central catheter with mediastinal abscess formation, which was successfully treated using a TMA. A 76-year-old woman developed a fever 3 months after the insertion of a peripherally inserted central catheter for parenteral nutrition. Imaging showed catheter tip migration with venous perforation, accompanied by abscess formation in the superior mediastinum. Owing to the anatomical difficulty in accessing this region, TMA was performed to remove the catheter and drain the abscess. The TMA provides optimal access while preserving neck and shoulder mobility, making it a suitable surgical option in older, frail patients.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** thoracic deformities (MESH:D013896), subclavian vessel injuries (MESH:C536223), emaciated (MESH:D004614), lung tumors (MESH:D008175), dyspnea (MESH:D004417), infection (MESH:D007239), leukocytosis (MESH:D007964), atrophy of the pectoralis major (MESH:C566793), vascular (MESH:D057772), phlebitis (MESH:D010689), vein thrombosis (MESH:D012170), inflammation (MESH:D007249), abscess (MESH:D000038), blood (MESH:D006402), fever (MESH:D005334), aspiration pneumonia (MESH:D011015), bleeding (MESH:D006470), mediastinal (MESH:D008480), extravasation (MESH:D005119), hypoalbuminemia (MESH:D034141), osteomyelitis (MESH:D010019), pneumonia (MESH:D011014), subclavian artery aneurysms (MESH:D013349), perforation (MESH:D057112)
- **Chemicals:** PICC (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** A 24F

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12954186/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12954186/full.md

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Source: https://tomesphere.com/paper/PMC12954186