# Exploration of health inequalities in patients treated with home non-invasive ventilation - Associations with respiratory healthcare burden

**Authors:** Wiktoria N. Milczanowska, Achaya Rajkumar, Nicholas J. Williamson, Oluwadamilare Falade, Laura Elliott, Amit S. Patel, Kai K. Lee

PMC · DOI: 10.1177/14799731261425236 · Chronic Respiratory Disease · 2026-02-28

## TL;DR

This study finds health inequalities in patients using home non-invasive ventilation, linking factors like gender, age, BMI, and deprivation to healthcare burden.

## Contribution

The study identifies specific health inequalities in home NIV patients and their associations with respiratory healthcare burden.

## Key findings

- Patients with higher BMI had lower adherence to home NIV treatment.
- Females had more hospital bed days compared to males.
- Older patients had more respiratory-related hospital admissions.

## Abstract

Health inequalities affect many respiratory diseases. However, little is known about the extent or impact amongst patients treated with home non-invasive ventilation (NIV). This study explored health inequalities faced by these patients and associations with respiratory healthcare burden.

A retrospective cohort study was conducted on patients actively receiving home-NIV treatment. Data on patient demographics, hospital healthcare burden and NIV adherence was collected between 4 October 2021 to 4 October 2023, and their relationships were evaluated.

187 patients met the inclusion criteria. Total hospital bed days was higher in females than in males, (11.7 ± 27.0 days vs 5.2 ± 12.5 days, p = 0.039), and increasing age was positively associated with higher number of respiratory-related hospital admissions (r = 0.146, p = 0.048). There was a weak correlation between deprivation rank and number of NIV care appointments missed (r = −0.163, p = 0.031). A higher BMI (>40 kg/m2) was associated with lower daily home-NIV use (68.7% ± 4.9% vs 83.0% ± 3.1% nights NIV used, p = 0.012).

Patients with higher BMI had lower NIV adherence, females required more hospital bed days, older patients had more hospital admissions, and more deprived patients missed more hospital appointments.

## Full-text entities

- **Diseases:** OHS (MESH:D010845), sleep-disordered breathing (MESH:D012891), overweight (MESH:D050177), COPD (MESH:D029424), obesity (MESH:D009765), overlap syndrome (MESH:D000080445), emergency (MESH:D004630), OSA (MESH:D020181), CRF (MESH:D012131), ORCID iDs (MESH:C535742), mental health disorder (OMIM:603663), diabetes mellitus (MESH:D003920), COVID (MESH:D000086382), cardiovascular disease (MESH:D002318), Chronic respiratory diseases (MESH:D012140), death (MESH:D003643)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12954001/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12954001/full.md

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Source: https://tomesphere.com/paper/PMC12954001