# Colloidal lignin particles for Pickering emulsion stabilization: multifunctional properties and prospects for cosmetic applications

**Authors:** Giovana Colucci, Alírio Egídio Rodrigues, Maria Filomena Barreiro

PMC · DOI: 10.1007/s13659-026-00594-3 · Natural Products and Bioprospecting · 2026-03-03

## TL;DR

This review explores how colloidal lignin particles can stabilize emulsions and serve as sustainable, multifunctional ingredients in cosmetics.

## Contribution

The paper reviews recent advances in using colloidal lignin particles as Pickering emulsifiers and multifunctional cosmetic ingredients.

## Key findings

- Colloidal lignin particles (CLPs) can effectively stabilize Pickering emulsions without surfactants.
- CLPs offer antioxidant, UV-blocking, and antimicrobial properties suitable for cosmetic applications.
- Challenges remain in scaling up CLP production and ensuring long-term stability in formulations.

## Abstract

Lignin, the most abundant aromatic biopolymer on Earth, is abundantly found as a by-product of biomass processing industries. Lignin presents remarkable properties, including antioxidant, UV-blocking, thermal stability, and antimicrobial; thus being considered a valuable feedstock to replace synthetic and fossil-based resources. Colloidal lignin particles (CLPs) are a promising strategy to overcome technical barriers in lignin valorization and have attracted increasing interest to be applied as multifunctional ingredients into several fields, including agriculture, biomedical, construction, and more recently, cosmetics. For this latter, CLPs stand out as promising Pickering stabilizers, creating opportunities for the development of surfactant-free cosmetic formulations. This review provides a current state of lignin research, focusing on the production of CLPs and Pickering emulsions and the key factors influencing their formation and stability. Recent progress in CLPs-stabilized Pickering emulsions is thoroughly addressed. Furthermore, it highlights advances on the multifunctional attributes of CLPs, including antioxidant activity, UV shielding, and demonstrated safety for cosmetic applications. The review concludes by discussing current challenges and future research directions for advancing the use of CLPs as sustainable materials in cosmetic science.

## Full-text entities

- **Genes:** GPHB5 (glycoprotein hormone subunit beta 5) [NCBI Gene 122876] {aka B5, GPB5, ZLUT1}, CALML3 (calmodulin like 3) [NCBI Gene 810] {aka CLP}, MS4A1 (membrane spanning 4-domains A1) [NCBI Gene 931] {aka B1, Bp35, CD20, CVID5, FMC7, LEU-16}, SEC14L2 (SEC14 like lipid binding 2) [NCBI Gene 23541] {aka C22orf6, SPF, TAP, TAP1}
- **Diseases:** skin cancer (MESH:D012878), inflammatory (MESH:D007249), skin irritation (MESH:D012871), neurotoxic (MESH:D020258), allergic reactions (MESH:D004342), leukemia (MESH:D007938), carcinogenic (MESH:D011230), CLPs (MESH:D002288), sunburn (MESH:D013471), cytotoxic (MESH:D064420)
- **Chemicals:** styrene (MESH:D020058), water (MESH:D014867), zinc oxide (MESH:D015034), ethylhexyl triazone (MESH:C466618), Lignosulfonates (MESH:C001545), BHT (MESH:D002084), vanillin (MESH:C100058), vitamin C (MESH:D001205), octisalate (MESH:C103422), aldehyde (MESH:D000447), octocrylene (MESH:C088673), HO (MESH:D017665), NaOH (MESH:D012972), homosalate (MESH:C060446), hemicellulose (MESH:C007916), ethanol (MESH:D000431), paraffin (MESH:D010232), Gallic acid (MESH:D005707), O (MESH:D010100), sodium sulfide (MESH:C033479), chitosan (MESH:D048271), sugars (MESH:D000073893), carboxylic acid (MESH:D002264), ammonium (MESH:D064751), ethylene glycol (MESH:D019855), polymers (MESH:D011108), carbon (MESH:D002244), DPPH (MESH:C004931), titanium dioxide (MESH:C009495), phenylpropane (MESH:C024268), MCT (MESH:C000709826), avobenzone (MESH:C049935), Lignin (MESH:D008031), BHA (MESH:D002083), tetrahydrofuran (MESH:C018674), W (MESH:D014414), OH (MESH:C031356), sulfonate (MESH:D000476), ABTS (MESH:C002502), H (MESH:D006859), sulfite (MESH:D013447), cellulose (MESH:D002482), oxybenzone (MESH:C005290), calcium (MESH:D002118), ROS (MESH:D017382), magnesium (MESH:D008274), S (MESH:D013455), olive oil (MESH:D000069463), Fibenol (-), superoxide (MESH:D013481), hydrogen peroxide (MESH:D006861), sodium (MESH:D012964), thyme oil (MESH:C000713830), corn oil (MESH:D003314), thiols (MESH:D013438), coconut oils (MESH:D000074263), toluene (MESH:D014050), oil (MESH:D009821), acetone (MESH:D000096), carbohydrates (MESH:D002241)
- **Species:** Cenchrus purpureus (elephant grass, species) [taxon 154765], Eucalyptus (genus) [taxon 3932], Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** LLC — Mus musculus (Mouse), Malignant tumors of the mouse pulmonary system, Cancer cell line (CVCL_5653), A549 — Homo sapiens (Human), Lung adenocarcinoma, Cancer cell line (CVCL_0023), 3T3 — Mus musculus (Mouse), Spontaneously immortalized cell line (CVCL_0594), HaCaT. — Homo sapiens (Human), Spontaneously immortalized cell line (CVCL_0038)

## Full text

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## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12953817/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12953817/full.md

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Source: https://tomesphere.com/paper/PMC12953817