# Mitotic entry: Bora takes Polo to Aurora, and gives them a hug

## TL;DR

This paper explains how three new studies uncovered the structural details of how Aurora A, PLK1, and Bora work together to control the start of cell division.

## Contribution

The studies reveal new atomic-level structural insights into the interactions between Aurora A, PLK1, and Bora during mitotic entry.

## Key findings

- Structural details of Aurora A and PLK1 interactions with Bora were revealed.
- The studies show how these proteins collaborate to trigger timely mitosis.
- The findings provide a clearer understanding of the control system for cell division.

## Abstract

Cell division involves the complete reorganization of the cellular architecture, requiring precise coordination of cellular processes in space and time, but how does this control system work at the atomic level? Three new studies offer a glimpse under the hood, revealing structural details of the intricate interactions between Aurora A and PLK1 kinases and the co-factor Bora, and how they act together to trigger timely entry to mitosis.

Three new studies reveal structural details of the intricate interactions between Aurora A and PLK1 kinases and the co-factor Bora, and how they act together to trigger timely entry to mitosis.