# Academic Outcomes in Primary and Secondary School Students Prescribed Long-Acting Stimulants for ADHD Management

**Authors:** Chris Folkins, Chandy Somayaji, Simerpal K. Gill, James Ted McDonald

PMC · DOI: 10.1177/10870547251378169 · Journal of Attention Disorders · 2025-10-07

## TL;DR

This study finds that long-acting stimulant medication for ADHD improves academic outcomes and school attendance in K-12 students.

## Contribution

The study provides empirical evidence on the academic benefits of long-acting stimulants for ADHD in school settings.

## Key findings

- LAS treatment improved report card and exam scores in grades 9-12 compared to untreated ADHD students.
- LAS treatment reduced school absences and increased high school graduation rates.
- Students on LAS were more likely to transition to post-secondary education.

## Abstract

This study examines the impact of long-acting stimulant (LAS) pharmacotherapy for ADHD on academic outcomes among students in grades K-12 using retrospective analysis of administrative data.

ADHD diagnosis was identified based on ADHD management plans in school records, physician notes in billing records, and/or prescription records. Prescription records identified LAS-treated students (n = 15,544), excluding those treated with immediate/intermediate-acting stimulants or atomoxetine. A control group without ADHD (n = 204,681), and another with untreated ADHD (n = 27,880) were also identified. The following outcomes were examined using multivariate regression: report card scores, standardized assessment exam performance, graduation from high school, school attendance, and transition to post-secondary education.

ADHD was associated with lower average report card scores and provincial assessment exam scores and increased frequency of school absence among grades K-12, and decreased likelihood of high school graduation and transition to post-secondary education. LAS treatment was associated with improved report card (score estimate −4.93 Treated, −6.19 Untreated) and provincial assessment exam scores (percentile rank estimate −9.20 Treated, −11.50 Untreated) among grades 9 to 12, reduced absences among grades K-12 (absence rate estimate −3.33 Treated, 7.96 Untreated), and increased likelihood of graduation (OR of failure to graduate 1.39 Treated, 2.22 Untreated) and transition to post-secondary education (OR of no transition 0.77 Treated, 1.42 Untreated; reference = No ADHD group).

LAS pharmacotherapy is associated with improved academic performance, attendance, and likelihood of graduation and transition to post-secondary education.

## Linked entities

- **Diseases:** ADHD (MONDO:0007743)

## Full-text entities

- **Diseases:** School (MESH:D010698), ADHD (MESH:D001289)
- **Chemicals:** atomoxetine (MESH:D000069445), Long-Acting Stimulants (-)

## Full text

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## Figures

14 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12953683/full.md

## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC12953683/full.md

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Source: https://tomesphere.com/paper/PMC12953683