# The frequency response of networks as open systems

**Authors:** Amirhossein Nazerian, Malbor Asllani, Melvyn Tyloo, Wai Lim Ku, Francesco Sorrentino

PMC · DOI: 10.1038/s41467-026-68602-1 · Nature Communications · 2026-01-27

## TL;DR

The paper explores how the structure of networks influences whether signals are amplified or suppressed based on input and output nodes.

## Contribution

The paper introduces a novel framework using the H2-norm to quantify signal amplification in open networks.

## Key findings

- Biological and natural networks enhance signal passing.
- Engineered systems like power grids suppress signal propagation.
- Network structure and input-output node selection determine signal behavior.

## Abstract

Many biological, technological, and social systems can be effectively described as networks of interacting subsystems. Typically, these networks are not isolated objects, but interact with their environment through both signals and information that are received by specific nodes with an input function or released to the environment by other nodes with an output function. An important question is whether the structure of different networks, together with the particular selection of input and output nodes, is such that it favors the passing or blocking of such signals. For a given network and a given choice of the input and output nodes, the \documentclass[12pt]{minimal}
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				\begin{document}$${{{{\mathcal{H}}}}}_{2}$$\end{document}H2-norm provides a natural and general quantification of the extent to which input signals–whether deterministic or stochastic, periodic or arbitrary–are amplified. We analyze a diverse set of empirical networks and find that many naturally occurring systems, such as food webs, signaling pathways, and gene regulatory circuits, are structurally organized to enhance the passing of signals; in contrast, the structure of engineered systems like power grids appears to be intentionally designed to suppress signal propagation.

Complex networks interact with their environment through input and output nodes. Here, authors show how network structure and the choice of input-output nodes determine whether signals are suppressed or amplified, revealing how topology shapes signal transmission

## Full-text entities

- **Chemicals:** DAG (-)
- **Species:** PX clade (clade) [taxon 569578]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12953583/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12953583/full.md

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Source: https://tomesphere.com/paper/PMC12953583