# Percutaneous Radiofrequency Ablation Combined With Balloon Kyphoplasty for Painful Vertebral Metastasis and Acute Pathologic Compression Fracture: A Case Report

**Authors:** Renato Abu Hana, Ruben G Ortiz Cordero, Oswaldo A Guevara Tirado, Grit A Adler, Vinicius Adami Vayego Fornazari

PMC · DOI: 10.7759/cureus.102717 · Cureus · 2026-01-31

## TL;DR

A minimally invasive procedure combining radiofrequency ablation and balloon kyphoplasty rapidly relieved severe back pain in a cancer patient with a spinal fracture.

## Contribution

Demonstrates same-session RFA and balloon kyphoplasty as an effective treatment for painful vertebral metastases and acute fractures.

## Key findings

- The patient experienced complete pain relief within 24 hours after the procedure.
- The patient was able to walk independently post-procedure without complications.
- The treatment provided immediate spinal stabilization without spinal cord compression.

## Abstract

Painful vertebral bone metastases may result in pathologic compression fractures, severe mechanical back pain, and functional impairment. Conventional external beam radiotherapy is commonly used for palliation but is limited by delayed analgesic effects and the inability to address spinal instability. Minimally invasive image-guided techniques, such as percutaneous radiofrequency ablation (RFA) combined with vertebral cement augmentation (VCA), may provide rapid pain relief while restoring mechanical stability.

We report the case of a 66-year-old man with advanced lung cancer who presented with severe opioid-refractory low back pain. Magnetic resonance imaging demonstrated an acute L4 pathologic compression fracture with approximately 40% vertebral height loss and no evidence of spinal cord compression. The patient underwent a same-session image-guided percutaneous vertebral biopsy followed by RFA and balloon kyphoplasty. Pre-procedural pain severity was assessed using the Visual Analog Scale (VAS), with a score of 10/10. Within 24 hours after the intervention, the patient reported complete pain relief (VAS 0/10) and was able to ambulate independently, without procedural complications.

This case highlights same-session percutaneous RFA combined with VCA as a minimally invasive strategy capable of providing rapid pain relief and immediate spinal stabilization in selected patients with painful vertebral metastases and pathologic compression fractures without spinal cord compression.

## Linked entities

- **Diseases:** lung cancer (MONDO:0005138)

## Full-text entities

- **Diseases:** paresthesia (MESH:D010292), pathologic fractures (MESH:D005598), myalgias (MESH:D063806), incontinence (MESH:D014549), spinal instability (MESH:D043171), necrosis (MESH:D009336), back pain (MESH:D001416), Compression Fracture (MESH:D050815), vertebral fracture or collapse (MESH:D001261), Vertebral Metastasis (MESH:D009362), arthralgias (MESH:D018771), cEBRT (MESH:C563514), vertebral fracture (MESH:C535781), thrombocytopenia (MESH:D013921), low back pain (MESH:D017116), vertebral body fracture (MESH:C536543), analgesia (MESH:D000699), spinal cord compression (MESH:D013117), laryngeal neoplasm (MESH:D007822), Fracture (MESH:D050723), Painful (MESH:D010146), complication (MESH:D008107), inflammatory (MESH:D007249), metastatic (MESH:D000092182), height (MESH:C000719188), lung cancer (MESH:D008175), Spinal Instability Neoplastic (MESH:D013125), cancer (MESH:D009369), weakness (MESH:D018908)
- **Chemicals:** steroids (MESH:D013256), bisphosphonates (MESH:D004164), morphine (MESH:D009020), VCA (-), lidocaine (MESH:D008012), fentanyl (MESH:D005283), polymethylmethacrylate (MESH:D019904), saline (MESH:D012965)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12952515/full.md

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Source: https://tomesphere.com/paper/PMC12952515