# Gastrointestinal endoscopy for intestinal dysplasia and neoplasia detection and management in Crohn’s disease: when and how?

## TL;DR

This review discusses how endoscopy helps detect and manage cancer risks in Crohn’s disease patients, focusing on when and how to use different techniques.

## Contribution

The paper provides practical guidance on endoscopic techniques for cancer prevention in Crohn’s disease, highlighting emerging technologies.

## Key findings

- Endoscopy is central for detecting dysplasia and early cancer in Crohn’s disease patients.
- Patients with Crohn’s disease have increased risks of colorectal and small bowel cancers.
- Emerging endoscopic technologies may improve cancer detection and management.

## Abstract

Patients with long-standing inflammatory bowel disease (IBD) involving the colon have an approximately 2–3-fold risk of colorectal cancer (CRC), which remains a leading cause of mortality in this population. However, data specifically assessing CRC incidence in Crohn’s disease (CD) are limited, and these patients also face an increased risk of small bowel cancer (SBC). Endoscopy plays a central role in CRC prevention, as well as in the detection and management of dysplasia and early CRC in CD. This review summarizes current evidence on the role of lower gastrointestinal endoscopy, as well as small bowel capsule endoscopy and device assisted enteroscopy, in this context. It provides practical guidance on the optimal use of these endoscopic techniques, considering patient- and disease-specific factors. Additionally, it highlights emerging endoscopic technologies and future perspectives in the field.