# A Case Report of Laparoscopic Cholecystectomy in an Obese Patient With Situs Inversus Totalis

**Authors:** Shohei Maruta, Tetsuro Ohno, Masami Yamada, Chiaki Fukuda, Akira Maki

PMC · DOI: 10.7759/cureus.104537 · Cureus · 2026-03-02

## TL;DR

This paper reports a successful laparoscopic cholecystectomy in an obese patient with a rare condition where internal organs are mirrored.

## Contribution

The case demonstrates the feasibility of laparoscopic cholecystectomy in obese patients with situs inversus totalis.

## Key findings

- Laparoscopic cholecystectomy was safely performed using a mirror-image port placement.
- The patient had an uneventful postoperative recovery.
- The procedure is viable for patients with both obesity and situs inversus totalis.

## Abstract

Situs inversus totalis (SIT) is a rare congenital condition characterized by a complete mirror-image arrangement of the visceral organs. We report a laparoscopic cholecystectomy performed on an obese patient with a body mass index (BMI) over 30 kg/m² and SIT. An 80-year-old female patient with SIT and a BMI of 30.1 kg/m² was diagnosed with cholecystolithiasis. Laparoscopic cholecystectomy was performed using a mirror-image port placement relative to the standard configuration. The postoperative course was uneventful. Laparoscopic cholecystectomy can be safely performed in patients with SIT, even in those with obesity, defined as a BMI greater than 30 kg/m².

## Linked entities

- **Diseases:** cholecystolithiasis (MONDO:0006698), situs inversus totalis (MONDO:0010029), obesity (MONDO:0011122)

## Full-text entities

- **Genes:** SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, ALPP (alkaline phosphatase, placental) [NCBI Gene 250] {aka ALP, PALP, PLAP, PLAP-1}, LOC102724197 (inactive glutathione hydrolase 2) [NCBI Gene 102724197] {aka GGT2}
- **Diseases:** cholecystectomy (MESH:D017562), asthma (MESH:D001249), blood loss (MESH:D016063), common bile duct injury (MESH:D003137), acute cholecystitis (MESH:D041881), infections (MESH:D007239), malignancy (MESH:D009369), gallstone (MESH:D042882), left upper quadrant pain (MESH:D010146), SIT (MESH:D012857), tree (MESH:D021184), bronchiectasis (MESH:D001987), sinusitis (MESH:D012852), Kartagener's syndrome (MESH:D007619), inflammation (MESH:D007249), condition (MESH:D020763), CVS (MESH:D016638), cholecystolithiasis (MESH:D041761), visceral transposition (MESH:D007418), bile duct injury (MESH:D001649), polysplenia (MESH:D059446), biliary colic (MESH:D003085), cholelithiasis (MESH:D002769), cardiovascular, renal, and biliary abnormalities (MESH:D018376), autosomal-recessive genetic disorder (MESH:D030342), overweight (MESH:D050177), pneumonia (MESH:D011014), cholecystitis (MESH:D002764), contrast allergy (MESH:D005119), dextrocardia (MESH:D003914), mucosal lesions (MESH:D009059), bleeding (MESH:D006470), Obese (MESH:D009765)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12951805/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12951805/full.md

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Source: https://tomesphere.com/paper/PMC12951805