# Safety and efficacy of a feed additive consisting of alpha‐galactosidase (produced with Aspergillus tubingensis ATCC SD 6740) and endo‐1,4‐beta‐xylanase (produced with Trichoderma orientale CBS 139997) (Capsozyme SB Plus) for weaned piglets (Industrial Técnica Pecuaria, S.A.)

## TL;DR

This paper evaluates the safety and effectiveness of a feed additive for weaned piglets, concluding it is safe and effective at the recommended dosage.

## Contribution

The paper provides a scientific assessment of Capsozyme SB Plus for use in weaned piglets, extending its authorization from poultry.

## Key findings

- The additive is safe for weaned piglets at the recommended inclusion level.
- The additive is efficacious in improving digestibility in weaned piglets.
- The additive poses a risk as a respiratory sensitiser due to inhalation exposure.

## Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a preparation containing alpha‐galactosidase and endo‐1,4‐beta‐xylanase (Capsozyme SB Plus) as a zootechnical feed additive (functional group: digestibility enhancers). The additive is already authorised for use in feed for chickens for fattening, chickens reared for laying, minor poultry species for fattening and reared for laying and ornamental birds. The applicant is seeking an extension of use to weaned piglets at a recommended inclusion level of 20 alpha‐galactosidase activity units (GALU) and 25 endo‐1,4‐beta‐xylanase activity units (AXC) per kg of complete feed. Based on the results of a tolerance study in weaned piglets, the FEEDAP Panel concluded that the additive is considered safe at the recommended inclusion level for weaned piglets. The Panel also concluded that the use of the feed additive in weaned piglets under the proposed conditions of use is considered safe for consumers and the environment. Regarding user safety, Capsozyme SB Plus is considered a respiratory sensitiser and exposure by inhalation is considered a risk. No conclusions could be reached on the potential of the additive to be irritant to the skin or eyes or a skin sensitiser. Based on the data provided by the applicant, the FEEDAP Panel concluded that Capsozyme SB Plus is efficacious in weaned piglets at the proposed use level of 20 GALU and 25 AXC units per kg complete feed.