# Massive Ovarian Edema Presenting With Abnormal Uterine Bleeding: A Case Report

**Authors:** Harneet S Randhawa, Aradhana A Shanmughan

PMC · DOI: 10.7759/cureus.102691 · Cureus · 2026-01-31

## TL;DR

This case report describes a rare benign ovarian condition that was misdiagnosed as a tumor but correctly identified using MRI.

## Contribution

The novelty lies in adding a rare clinical case of massive ovarian edema with abnormal uterine bleeding to the literature.

## Key findings

- Massive ovarian edema was diagnosed in a young woman after initial imaging was inconclusive.
- MRI confirmed the diagnosis and prevented unnecessary surgery.
- The case highlights the importance of considering rare conditions in differential diagnosis.

## Abstract

Massive ovarian edema (MOE) is a rare, tumor-like, benign condition characterized by diffuse ovarian enlargement. It is mostly associated with partial/intermittent adnexal torsion, resulting in impaired venous and lymphatic drainage of the ovaries. Owing to its nonspecific clinical presentation and tumor-like imaging appearance, MOE is often misdiagnosed as an ovarian neoplasm, leading to unnecessary oophorectomies. We report a case of MOE in a young nulligravid woman who presented with abnormal uterine bleeding. Following an initial inconclusive clinical evaluation and ultrasonography, the diagnosis was eventually confirmed by magnetic resonance imaging (MRI) of the pelvis, and appropriate treatment could be undertaken. Due to the rarity of incidence and atypical presentation, we would like to add this case to the existing scientific literature.

## Full-text entities

- **Genes:** MUC16 (mucin 16, cell surface associated) [NCBI Gene 94025] {aka CA125}, AFP (alpha fetoprotein) [NCBI Gene 174] {aka AFPD, FETA, HPAFP}, CEACAM3 (CEA cell adhesion molecule 3) [NCBI Gene 1084] {aka CD66D, CEA, CGM1, CGM1a, W264, W282}
- **Diseases:** weight loss (MESH:D015431), infertility (MESH:D007246), polycystic ovarian syndrome (MESH:D011085), pelvic pain (MESH:D017699), Ascites (MESH:D001201), Uterine Bleeding (MESH:D014592), adnexal torsion (MESH:D000082843), cysts (MESH:D003560), ovarian (MESH:D010049), necrosis (MESH:D009336), Meigs' syndrome (MESH:D008538), MOE (MESH:D010051), abdominal or pelvic tenderness (MESH:D000007), abdominal pain (MESH:D015746), edema (MESH:D004487), Tumor (MESH:D009369), calcification (MESH:D002114), torsion (MESH:D050723), hirsutism (MESH:D006628), pelvic mass lesion (MESH:C536030), fever (MESH:D005334), bleeding (MESH:D006470)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12951532/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12951532/full.md

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Source: https://tomesphere.com/paper/PMC12951532