# First-Attempt Intubation Success Rate Using the C-MAC Videolaryngoscope Versus Direct Laryngoscopy Among Anaesthesiology Residents Performing Rapid Sequence Induction: A Randomised Controlled Trial

**Authors:** Penumaka Lava Kumar, Sakthirajan Panneerselvam, Santhosh Arulprakasam, Priya Rudingwa, Ranjithkumar Mekala, Prasanna U Bidkar

PMC · DOI: 10.7759/cureus.102723 · Cureus · 2026-01-31

## TL;DR

This study found that using a videolaryngoscope improved first-time success rates for intubation among trainee anesthesiologists during emergency procedures.

## Contribution

Demonstrated superior first-attempt intubation success with videolaryngoscopy versus direct laryngoscopy in novice residents during rapid sequence induction.

## Key findings

- Videolaryngoscope group had 93% first-attempt success versus 67% with direct laryngoscopy
- Fewer adjunct maneuvers and airway injuries occurred with videolaryngoscopy
- Better laryngeal views were achieved using videolaryngoscopy

## Abstract

Background and aims: The primary objective of this randomised trial was to compare the first-attempt intubation success rate between the C-MAC videolaryngoscope (VL) and the Macintosh direct laryngoscope (DL) when used by novice anaesthesia residents during rapid sequence induction (RSI). Secondary objectives were to compare intubation time; laryngoscopic view (Cormack-Lehane grade (CLG) and Percentage of Glottic Opening (POGO) score); the need for adjunct manoeuvres and devices (optimal external laryngeal manipulation (OELM), release of cricoid pressure, and use of a gum elastic bougie (GEB)); and the incidence of hypoxia, regurgitation, mucosal or dental injury, and haemodynamic changes during and after intubation.

Methods: This randomised controlled trial included 172 adult patients with normal airways requiring RSI, who were allocated to either the VL group (n = 86) or the DL group (n = 86). Resident anaesthesiologists underwent lecture- and simulation-based training prior to performing intubations in the operating room. RSI and tracheal intubation were performed using the allocated device. The primary endpoint was first-attempt intubation success. Secondary endpoints included intubation time, manoeuvres required for successful intubation, incidence of hypoxia and regurgitation, mucosal or dental injury, and haemodynamic changes during and after intubation.

Results: First-attempt intubation success was significantly higher in the VL group compared with the DL group (93% vs 67%, P < 0.001). A CLG 1 view was obtained in 76% of patients in the VL group and 54% in the DL group (P < 0.001). External laryngeal manipulation, release of cricoid pressure, use of a GEB, and dental injuries were significantly lower in the VL group (P < 0.001). Heart rate and systolic blood pressure increased significantly during DL-guided intubation.

Conclusion: VL-guided intubation by novice anaesthesia residents during RSI was associated with a higher first-attempt success rate and superior laryngoscopic views compared with DL, along with fewer adjunct manoeuvres and airway injuries. These findings support the use of VL as a valuable tool for resident-performed RSI in patients without anticipated difficult airways.

## Full-text entities

- **Diseases:** Mucosal injuries (MESH:D052016), OSA (MESH:D020181), Dental injuries (MESH:D009057), CLG 1 (MESH:D008224), cervical spine injury (MESH:D002575), hypoxemia (MESH:D000860), airway injuries (MESH:D000402), hypotension (MESH:D007022), DL (MESH:D051556), obese (MESH:D009765), OELM (MESH:D007827), critically ill (MESH:D016638), mucosal or dental trauma (MESH:D014947)
- **Chemicals:** succinylcholine (MESH:D013390), rocuronium (MESH:D000077123), lidocaine (MESH:D008012), DL (-), propofol (MESH:D015742), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12950991/full.md

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Source: https://tomesphere.com/paper/PMC12950991