# Bronchial Atresia Presenting With Recurrent Pneumonia in an Adult With Asthma: The Importance of Post-infectious Radiological Reassessment

**Authors:** Gonçalo Carneiro, Rita Aranha, Bernardo Macedo

PMC · DOI: 10.7759/cureus.102738 · Cureus · 2026-01-31

## TL;DR

A 39-year-old woman with asthma developed recurrent pneumonia, and post-infectious imaging revealed a rare bronchial anomaly, highlighting the need for follow-up scans in such cases.

## Contribution

Demonstrates that bronchial atresia can present in adults with atypical locations and emphasizes the importance of post-infectious radiological reassessment.

## Key findings

- Recurrent pneumonia in an adult led to the discovery of bronchial atresia in an atypical location.
- Post-infectious CT imaging was crucial in identifying the structural anomaly.
- Conservative management was chosen after multidisciplinary evaluation.

## Abstract

Congenital bronchial atresia (CBA) is a rare developmental anomaly characterized by focal obliteration of a segmental bronchus. It is typically asymptomatic and discovered incidentally; however, symptomatic presentations with recurrent respiratory infections have been reported, particularly in pediatric populations.

We report a 39-year-old woman with well-controlled asthma who developed recurrent left lower lobe pneumonia following COVID-19 infection. Despite appropriate antibiotic therapy, she required hospitalization due to clinical recrudescence. Initial computed tomography (CT) demonstrated active inflammatory changes, while reassessment CT after clinical resolution revealed a mucus-filled, finger-like structure extending from the hilum without communication with the bronchial tree, along with regional emphysema, findings consistent with bronchial atresia of the left lower lobe, an atypical location. Conservative management was adopted following multidisciplinary discussion. This case highlights the importance of considering structural bronchial anomalies in recurrent localized pneumonia and demonstrates that bronchial atresia may present symptomatically in adults with unusual anatomical distributions, reinforcing the value of appropriately timed post-infectious radiological reassessment.

## Linked entities

- **Diseases:** asthma (MONDO:0004979), pneumonia (MONDO:0005249), COVID-19 (MONDO:0100096)

## Full-text entities

- **Genes:** GGTLC5P (gamma-glutamyltransferase light chain 5 pseudogene) [NCBI Gene 653590] {aka GGT}, GPT (glutamic--pyruvic transaminase) [NCBI Gene 2875] {aka AAT1, ALT, ALT1, GPT1, SGPT}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}, GGT1 (gamma-glutamyltransferase 1) [NCBI Gene 2678] {aka CD224, D22S672, D22S732, GGT, GGT 1, GGTD}
- **Diseases:** ischemic (MESH:D002545), pulmonary abnormalities (MESH:D008171), malignancy (MESH:D009369), cyanosis (MESH:D003490), dyspnea (MESH:D004417), Asthma (MESH:D001249), emphysema (MESH:D004646), vascular insufficiency (MESH:D065666), congenital anomaly (MESH:D000013), congenital pulmonary malformations (MESH:D009421), respiratory infections (MESH:D012141), airway inflammation (MESH:D007249), impaired immunity (MESH:D020274), CBA (MESH:D002283), respiratory diseases (MESH:D012140), fever (MESH:D005334), respiratory distress (MESH:D012128), pulmonary embolism (MESH:D011655), ischemia (MESH:D007511), hemoptysis (MESH:D006469), Pneumonia (MESH:D011014), chest pain (MESH:D002637), clubbing (MESH:D003025), COVID-19 (MESH:D000086382), allergic rhinitis (MESH:D065631), sterility (MESH:D007246), pneumothorax (MESH:D011030), infection (MESH:D007239), leukocytosis (MESH:D007964), cough (MESH:D003371), dysphagia (MESH:D003680), viral infection (MESH:D014777), Bronchial Atresia (MESH:D001982), HIV (MESH:D015658), post-COVID (MESH:D000094024), infectious (MESH:D003141), emphysematous (MESH:D041882), neurological impairment (MESH:D009422), developmental anomaly (MESH:C566440), aspiration (MESH:D011015), mediastinal lymphadenopathy (MESH:D008477)
- **Chemicals:** amoxicillin-clavulanate (MESH:D019980), lactate (MESH:D019344), formoterol (MESH:D000068759), azithromycin (MESH:D017963), oxygen (MESH:D010100), piperacillin-tazobactam (MESH:D000077725), HCO3 (MESH:D001639), prednisolone (MESH:D011239), respiratory irritants (-), Na (MESH:D012964), montelukast (MESH:C093875), K (MESH:D011188), glucose (MESH:D005947), budesonide (MESH:D019819)
- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Homo sapiens (human, species) [taxon 9606], Human immunodeficiency virus (species) [taxon 12721]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12950985/full.md

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Source: https://tomesphere.com/paper/PMC12950985