# A Rare Case of an Isolated Interventricular Septal Hydatid Cyst Presenting With Atrioventricular Block in a Non-endemic Region

**Authors:** Mehran Jalilzadehbinazar, Maged Y Haikal, Matthew L German, Jeremy E Leidenfrost, Anupama K Rao

PMC · DOI: 10.7759/cureus.102673 · Cureus · 2026-01-30

## TL;DR

A rare case of a heart cyst caused by a parasite in a non-endemic region was successfully treated with surgery and medication.

## Contribution

This case report presents a rare instance of an isolated interventricular septal hydatid cyst causing AV block in a non-endemic region.

## Key findings

- A 41-year-old male presented with AV block and a large cystic mass in the basal IVS confirmed by imaging.
- Surgical excision and albendazole therapy led to successful recovery.
- The case underscores the importance of considering hydatid disease in differential diagnosis despite non-endemic location.

## Abstract

Cardiac involvement in human echinococcosis is rare, with isolated interventricular septal (IVS) cysts representing an uncommon presentation. This report details the case of a 41-year-old male who presented to urgent care with fever, cough, and exertional dyspnea. Initial evaluation revealed high-grade atrioventricular (AV) block and markedly elevated inflammatory markers. Advanced cardiac imaging (echocardiography, CT, and MRI) identified a large, complex cystic mass within the basal IVS. Serology was positive for Echinococcus antibody, and a history of residence in an endemic region with contact with stray dogs provided epidemiological support. The patient underwent successful surgical excision of the cyst followed by adjuvant albendazole therapy, with an uncomplicated recovery. This case highlights the diagnostic challenge of cardiac hydatid disease, which can mimic sepsis or myocarditis, and emphasizes the critical role of multimodal imaging and exposure history in guiding diagnosis. Given the risk of life-threatening complications, timely surgical intervention combined with medical therapy is essential for management.

## Linked entities

- **Chemicals:** albendazole (PubChem CID 2082)
- **Diseases:** echinococcosis (MONDO:0005738), atrioventricular block (MONDO:0000465), myocarditis (MONDO:0004496)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** pulmonary infection (MESH:D012141), Cardiac hydatidosis (MESH:D004443), abscesses (MESH:D000038), Inflammatory (MESH:D007249), flank pain (MESH:D021501), Cyst rupture (MESH:D012421), valvular dysfunction (MESH:D006349), ischemic (MESH:D002545), calcification (MESH:D002114), tumors (MESH:D009369), cystic neoplasm (MESH:D018297), dyspnea (MESH:D004417), blood eosinophilia (MESH:D004802), arrhythmias (MESH:D001145), febrile (MESH:D000071072), acute myocarditis (MESH:D009205), fatigue (MESH:D005221), chest pain (MESH:D002637), IVS (MESH:C563239), heart block (MESH:D006327), febrile illness (MESH:D005334), systemic or pulmonary embolism (MESH:D011655), intraventricular septal mass (MESH:D006345), hypotensive (MESH:D007022), anaphylactic shock (MESH:D000707), outflow tract obstruction (MESH:D000092243), infection (MESH:D007239), AV block (MESH:D054537), cough (MESH:D003371), congestive heart failure (MESH:D006333), conduction disturbances (MESH:C563984), abdominal echinococcosis (MESH:D000007), embolism (MESH:D004617), Cardiac (MESH:D006331), parasitic infection (MESH:D010272), intracardiac mass (MESH:C538262), sepsis (MESH:D018805), pericardial tamponade (MESH:D002305), cardiac cyst (MESH:D003560), Infectious (MESH:D003141)
- **Chemicals:** hypertonic saline (MESH:D012965), silver nitrate (MESH:D012835), PSIR (-), Albendazole (MESH:D015766), gadolinium (MESH:D005682), iodine (MESH:D007455)
- **Species:** Echinococcus (genus) [taxon 6209], Canis lupus familiaris (dog, subspecies) [taxon 9615], Echinococcus granulosus (species) [taxon 6210], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12950814/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12950814/full.md

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Source: https://tomesphere.com/paper/PMC12950814