# The impact of COVID-19 on blood supply–demand balance and the association between group donations and economic performance: evidence from Zhejiang, China

**Authors:** Guan Wang, Xiaoying Pu, Renzo Jose Carlos Calderon Anyosa, Yaming Gu

PMC · DOI: 10.3389/fpubh.2026.1739767 · Frontiers in Public Health · 2026-02-16

## TL;DR

The study shows how the COVID-19 pandemic disrupted blood supply and demand in China, especially for blood types A and O, and how blood donations relate to local economic performance.

## Contribution

The study provides new evidence on how specific blood types were impacted by the pandemic and their link to economic performance.

## Key findings

- The pandemic caused a sharp drop in the blood supply-to-demand ratio, most severe for blood types A and O.
- Group donations were positively linked to local economic performance, though this link weakened during the pandemic.

## Abstract

The COVID-19 pandemic significantly disrupted the balance between blood supply and demand; however, limited evidence reveals how this imbalance emerged, particularly across specific blood types. Changes in donation patterns during the pandemic and their association with the local economy also remain underexplored.

Using provincial-level data from 2014 to 2023, we used an interrupted time series model to analyze the trends in blood supply, blood demand, and group donations caused by the pandemic. Generalized least squares and distributed lag models were applied to examine the relationship between group donations and local economic performance.

The pandemic led to an immediate decline in the supply-to-demand ratio for blood, with types A and O most severely affected. Group donations were positively associated with local economic performance, although COVID-19 attenuated this relationship.

Tailored strategies are needed for blood types in high demand. Supporting group donations may help promote economic resilience during public health crises.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Genes:** ABO (ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase) [NCBI Gene 28] {aka A3GALNT, A3GALT1, GTA, GTB, NAGAT}
- **Diseases:** type AB (MESH:D049290), COVID (MESH:D000086382), infection (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12950710/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12950710/full.md

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Source: https://tomesphere.com/paper/PMC12950710