# Unilateral diaphragmatic paralysis following cervical spine surgery in a patient with neurological symptoms: a case report and review of the literature

**Authors:** Kai Chen, Jiafu Zhu

PMC · DOI: 10.3389/fphys.2026.1685728 · Frontiers in Physiology · 2026-02-16

## TL;DR

A 74-year-old man developed breathing issues after cervical spine surgery, likely due to phrenic nerve damage, and showed improvement with conservative treatment.

## Contribution

This case report highlights unilateral diaphragmatic paralysis as a rare complication of cervical spine surgery in a patient with neurological symptoms.

## Key findings

- Postoperative imaging showed right-sided diaphragmatic elevation, indicating phrenic nerve dysfunction.
- Conservative treatment led to significant improvement in respiratory symptoms within six weeks.
- Neurological symptoms should prompt early recognition of phrenic nerve involvement to prevent complications.

## Abstract

Unilateral diaphragmatic paralysis is an extremely rare postoperative complication following cervical spine surgery. We present a case of unilateral diaphragmatic paralysis following cervical spine surgery in a patient with preoperative neurological symptoms and discuss the related literature.

A 74-year-old male presented with gait instability and frequent falls. Postoperatively, the patient developed dyspnea.

Postoperative imaging revealed right-sided diaphragmatic elevation, indicating phrenic nerve dysfunction. Cervical myelopathy at C3/4 and C4/5 levels was identified as a relevant underlying condition during the determination of the postoperative course.

The patient underwent anterior cervical discectomy and fusion (ACDF) at C3/4 and C4/5. Conservative management, including oxygen therapy and neurotrophic support, was provided postoperatively.

Significant improvement in respiratory symptoms was observed by postoperative Day 42, with a reduction in right hemidiaphragm elevation on chest computed tomography (CT). The patient’s dyspnea gradually improved with treatment, and respiratory function stabilized.

This case highlights the need to monitor for respiratory complications after cervical spine surgery, even in patients without preoperative respiratory symptoms. Neurological signs should prompt early recognition of phrenic nerve involvement to prevent further complications and improve outcomes.

## Full-text entities

- **Diseases:** disc protrusion (MESH:D007405), Cervical myelopathy (MESH:D002575), Unilateral diaphragmatic paralysis (MESH:D012133), difficulty (MESH:D051346), foraminal stenosis (MESH:D003251), neurological deficits (MESH:D009461), spinal cord dysfunction (MESH:D013118), gait instability (MESH:D043171), respiratory distress (MESH:D012128), bronchospasm (MESH:D001986), chest tightness (MESH:D002637), paralysis (MESH:D010243), diaphragm dysfunction (MESH:D065630), pleural effusion (MESH:D010996), respiratory difficulties (MESH:D012131), pulmonary infiltrates (MESH:D017254), hemorrhage (MESH:D006470), nerve involvement (MESH:C564676), nerve root compression (MESH:D011843), Cervical spondylosis (MESH:D055009), cough (MESH:D003371), edema (MESH:D004487), diaphragmatic dysfunction (MESH:D056989), dyspnea (MESH:D004417), infection (MESH:D007239), psychiatric (MESH:D001523), neurogenic damage (MESH:D001750), postoperative complication (MESH:D011183), motor and sensory deficits (MESH:D001289), motor weakness (MESH:D018908), respiratory complications (MESH:D012140), death (MESH:D003643), radicular pain (MESH:D010146), Sleep difficulties (MESH:D012893), phrenic nerve damage (MESH:D000080902), Parkinson's disease (MESH:D010300), inflammation (MESH:D007249), complications (MESH:D008107), Phrenic nerve dysfunction (MESH:D005155), degenerative conditions of the cervical spine (MESH:D019636), ACDF (MESH:D007714)
- **Chemicals:** methylprednisolone (MESH:D008775), cephalosporins (MESH:D002511), dexamethasone (MESH:D003907), theophylline (MESH:D013806), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12950605/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12950605/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12950605/full.md

---
Source: https://tomesphere.com/paper/PMC12950605