Continuing Professional Development – Radiation Therapy
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TopicsAdvances in Oncology and Radiotherapy · Effects of Radiation Exposure · Management of metastatic bone disease
Maximise your continuing professional development (CPD) by reading the selected article and answering the five questions. Please remember to self‐claim your CPD and retain your supporting evidence. Answers will be available via the QR code and published in JMRS – Volume 73, Issue 4, December 2026.
Magnetic Resonance Guided Radiation Therapy (MRgRT) Prostate Motion and Margins
Sammi Peng, Tegan Courtot, Jessica Lye, Farshad Foroudi, Mark Tacey, Daryl Lim Joon, Michael Chao, Ee Siang Choong, https://doi.org/10.1002/jmrs.70033.
- Which factor is the main contributor to prostate motion during MR‐guided radiotherapy (MRgRT)?
- Variations in magnetic field strength
- Bladder filling and rectal gas movement
- Patient anxiety
- Respiratory motion
- During adaptive MRgRT, why is real‐time motion monitoring particularly critical during the adaptation phase?
- Prolonged contour adjustment and plan recalculation allow natural organ shift.
- Rapid beam‐on delivery causes sudden prostate shifts.
- Fusion planning during adaptation deforms prostate.
- Respiratory motion peaks during adaptation.
- How does cine‐MRI motion monitoring improve treatment safety and accuracy during MRgRT?
- Reduces MR scan time.
- Repositions CTV in real time to maintain coverage.
- Adjusts radiation dose dynamically during beam‐on.
- Allows treatment interruption if displacement exceeds PTV margins.
- Which MRgRT feature best enables precise prostate dose delivery while minimising toxicity to surrounding organs?
- Higher dose rates per fraction.
- Faster image acquisition sequences
- Superior soft tissue visualisation and organ delineation
- No image registration required
- Based on the findings of this study, what margins could be considered most appropriate for prostate MRgRT?
- 1–2 mm isotropic margins
- 5–8 mm isotropic margins
- 2–3 mm non‐isotropic margins
- 8–10 mm non‐isotropic margins
Answers
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The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1A. Mannerberg , E. Persson , J. Jonsson , et al., “Dosimetric Effects of Adaptive Prostate Cancer Radiotherapy in an MR‐Linac Workflow,” Radiation Oncology 15 (2020): 1–9, 10.1186/s 13014-020-01604-5.PMC 735059332650811 · doi ↗ · pubmed ↗
- 2A. U. Kishan , T. M. Ma , J. M. Lamb , et al., “Magnetic Resonance Imaging–Guided vs Computed Tomography–Guided Stereotactic Body Radiotherapy for Prostate Cancer: The MIRAGE Randomised Clinical Trial,” JAMA Oncology 9, no. 3 (2023): 365–373, 10.1001/jamaoncol.2022.6558.36633877 PMC 9857817 · doi ↗ · pubmed ↗
- 3M. G. Dassen , T. Janssen , M. Kusters , et al., “Comparing Adaptation Strategies in MRI‐Guided Online Adaptive Radiotherapy for Prostate Cancer: Implications for Treatment Margins,” Radiotherapy and Oncology 20 (2023): 109761, 10.1016/j.radonc.2023.109761.37348607 · doi ↗ · pubmed ↗