# Laparoscopic Resection for Rectal Cancer in a Centenarian: A Case Report Highlighting the Importance of Functional Independence over Chronological Age

**Authors:** Asahi Tokinaga, Fuminori Teraishi, Naoki Onoda, Koki Omoto, Ryusei Takahashi, Hiroki Okabayashi, Masashi Utsumi, Hideaki Miyaso, Shinya Otsuka, Masaru Inagaki

PMC · DOI: 10.70352/scrj.cr.25-0653 · Surgical Case Reports · 2026-02-26

## TL;DR

A 100-year-old woman successfully underwent laparoscopic surgery for rectal cancer, showing that age alone should not prevent such procedures.

## Contribution

Demonstrates the feasibility of elective laparoscopic resection in a centenarian using geriatric assessments to guide surgery.

## Key findings

- The patient had excellent functional independence and physiological fitness preoperatively.
- Laparoscopic surgery was completed without complications and with negative resection margins.
- The patient recovered well and was discharged on postoperative day 12.

## Abstract

Laparoscopic resection for rectal cancer in a centenarian is extraordinarily rare, with only a few cases of elective curative surgery reported worldwide. As the global population ages, the number of centenarians with malignancies is increasing; however, surgical intervention in this age group remains controversial due to frailty and limited physiological reserve.

We present the case of a 100-year-old female with Stage IIIB rectal cancer who successfully underwent elective laparoscopic low anterior resection. Comprehensive preoperative geriatric assessments—comprising the Geriatric-8 (G8), instrumental activities of daily living (IADL), and EuroQol-5 dimensions (EQ-5D and EQ-VAS)—demonstrated excellent functional independence and physiological fitness. Despite severe intra-abdominal adhesions from a prior laparotomy, meticulous laparoscopic adhesiolysis and tumor-specific mesorectal excision were achieved without complications. Twelve lymph nodes were retrieved, with one positive node, and all resection margins were negative. The patient recovered uneventfully, retained postoperative independence, and was discharged on POD 12.

This case highlights that functional and biological fitness—rather than chronological age—should guide surgical decision-making in the oldest-old population. It also underscores the feasibility and safety of minimally invasive curative surgery for selected centenarians when supported by detailed geriatric evaluation and multidisciplinary planning.

## Linked entities

- **Diseases:** rectal cancer (MONDO:0006519)

## Full-text entities

- **Genes:** ALB (albumin) [NCBI Gene 213] {aka FDAHT, HSA, PRO0883, PRO0903, PRO1341}
- **Diseases:** colorectal cancer (MESH:D015179), hypertension (MESH:D006973), adhesions (MESH:D000267), bowel obstruction (MESH:D012778), anemia (MESH:D000740), Rectal Cancer (MESH:D012004), blood loss (MESH:D016063), small bowel obstruction (MESH:D007409), PRESENTATION (MESH:D001946), abdominal pain (MESH:D015746), Stage IIIB disease (MESH:D007676), valvular disease (MESH:D006349), postoperative pain (MESH:D010149), cancer (MESH:D009369), tubular adenocarcinoma (MESH:D000230), tenderness (MESH:D063806), IIIB (MESH:C566890), serosal injury (MESH:D012700), abdominal distension (MESH:D000007), renal impairment (MESH:D007674), breast, prostate, and skin malignancies (MESH:D001943), cataracts (MESH:D002386), frailty (MESH:D000073496), cognitive impairment (MESH:D003072), intra-abdominal adhesions (MESH:D000082122)
- **Chemicals:** CGA (MESH:C554042), indocyanine green (MESH:D007208), creatinine (MESH:D003404)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12950480/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12950480/full.md

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Source: https://tomesphere.com/paper/PMC12950480