# The absence of the alpha-1 band in serum protein electrophoresis as a clue to diagnosis of alpha-1 antitrypsin deficiency panniculitis

**Authors:** Erica Dale, Frank Z. Jing, Michael Camilleri, Kenneth J. Warrington, Afsaneh Alavi

PMC · DOI: 10.1016/j.jdcr.2026.01.004 · JAAD Case Reports · 2026-01-10

## Full-text entities

- **Genes:** AAT1 (Aortic aneurysm, familial thoracic 1) [NCBI Gene 252842] {aka FAA1}, BCL2A1 (BCL2 related protein A1) [NCBI Gene 597] {aka ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1}, SERPINA1 (serpin family A member 1) [NCBI Gene 5265] {aka A1A, A1AT, AAT, PI, PI1, PRO2275}, PRTN3 (proteinase 3) [NCBI Gene 5657] {aka ACPA, AGP7, C-ANCA, CANCA, MBN, MBT}
- **Diseases:** antiprotease insufficiency (MESH:D000309), morbid (OMIM:614963), lung damage (MESH:D008171), ANCA vasculitis (MESH:D056648), emphysema (MESH:D004646), liver cirrhosis (MESH:D008103), fibrosis (MESH:D005355), inflammation (MESH:D007249), abscess (MESH:D000038), vasculitis (MESH:D014657), trauma (MESH:D014947), skin lesions (MESH:D012871), lipedema (MESH:D065134), fat (MESH:D004620), hemorrhage (MESH:D006470), obesity (MESH:D009765), cutaneous lesions (MESH:D009059), pleural effusions (MESH:D010996), systemic small vessel vasculitis (MESH:C565222), chronic obstructive pulmonary disease (MESH:D029424), gammopathy (MESH:D010265), AAT deficiency (MESH:D019896), lipodermatosclerosis (MESH:C537026), Panniculitis (MESH:D015434), neutrophilic (MESH:C564275), falciform ligament necrosis (MESH:D009336), dermal (MESH:D016136)
- **Chemicals:** doxycycline (MESH:D004318), Pi*S (MESH:D010716), GMS (MESH:C009032), Pi*Z. (-), Hematoxylin (MESH:D006416), eosin (MESH:D004801)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

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Source: https://tomesphere.com/paper/PMC12950424