# Lost to Follow-Up After Patent Foramen Ovale (PFO) Closure: Late Detection of Abdominal Aortic Embolization of an Occluder Device

**Authors:** Amir Hakanovic, Mirza Kovacevic, Minela Hadzic Abdurahmanovic, Igal Moarof

PMC · DOI: 10.7759/cureus.102632 · Cureus · 2026-01-30

## TL;DR

A rare case of a PFO closure device moving to the abdominal aorta five years after implantation is reported, emphasizing the need for long-term monitoring.

## Contribution

This paper presents a unique case of late embolization of a PFO occluder device and highlights the importance of long-term follow-up in complex cardiovascular cases.

## Key findings

- A PFO occluder device embolized to the suprarenal abdominal aorta five years after implantation.
- The patient remained asymptomatic despite the device migration, with no limb or renal hypoperfusion observed.
- Percutaneous retrieval was not feasible due to high risk, and the device was left in situ.

## Abstract

Embolization of a patent foramen ovale (PFO) occluder is a rare complication, particularly when detected years after device implantation. We report a case of a 30-year-old patient who initially presented with acute right lower limb ischemia caused by embolic occlusion of multiple arteries. A floating thrombus was detected in the inferior vena cava, and subsequent evaluation revealed a PFO, a bicuspid aortic valve, and an aortic arch anomaly. Six weeks later, PFO closure was performed using a 25 mm Amplatzer Cribriform device (Abbott, Chicago, Illinois), followed by appropriate post-procedural antithrombotic therapy. Nearly five years after implantation, routine follow-up revealed asymptomatic embolization of the occluder to the suprarenal abdominal aorta at the level of the superior mesenteric artery, without evidence of limb or renal hypoperfusion; the exact timing of embolization could not be determined. Percutaneous retrieval was attempted but aborted due to pain and the high risk of aortic injury, and the device was therefore left in situ. This case highlights a rare late complication of PFO closure and underscores the importance of long-term surveillance in patients with complex cardiovascular anatomy and thrombotic risk factors.

## Linked entities

- **Diseases:** patent foramen ovale (MONDO:0020439)

## Full-text entities

- **Diseases:** peripheral arterial embolism (MESH:D058729), embolic (MESH:D004617), aortic arch anomaly (MESH:C535542), organ injury (MESH:D009102), thromboembolic (MESH:D013923), paradoxical embolism (MESH:D019320), venous thrombi (MESH:D014647), thrombophilic (MESH:D019851), ischemia (MESH:D007511), intracardiac thrombi (MESH:C538262), stenosis (MESH:D003251), congenital cardiac anomaly (MESH:C535853), pulmonary embolism (MESH:D011655), cryptogenic stroke (MESH:D000083242), acute limb ischemia (MESH:D000208), Ovale (MESH:D054092), bicuspid aortic valve (MESH:D000082882), visceral hypoperfusion (MESH:D007418), intermittent claudication (MESH:D007383), atrial septal aneurysm (MESH:D006344), thrombotic (MESH:D013927), aortic injury (MESH:D001018), occlusion of the profunda femoris artery (MESH:D001157), flu (MESH:D007251), pain (MESH:D010146), infection (MESH:D007239), aortic rupture (MESH:D001019), arteries (MESH:D012078), ischemic (MESH:D002545), COVID-19 (MESH:D000086382), Atrial fibrillation (MESH:D001281), abdominal pain (MESH:D015746), antiphospholipid antibody syndrome (MESH:D016736)
- **Chemicals:** acetylsalicylic acid (MESH:D001241), rivaroxaban (MESH:D000069552), heparin (MESH:D006493), antithrombotic (-), clopidogrel (MESH:D000077144), dalteparin sodium (MESH:D017985)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12950293/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12950293/full.md

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Source: https://tomesphere.com/paper/PMC12950293