# Embolization therapy for pelvic arteriovenous malformations: a systematic review

**Authors:** Chiara Brechbühl, Nicolas Diehm, Hanno Hoppe

PMC · DOI: 10.1186/s42155-026-00667-x · CVIR Endovascular · 2026-02-28

## TL;DR

This paper reviews embolization therapy for pelvic arteriovenous malformations, showing it is effective and safe with high success rates.

## Contribution

The study provides a systematic review of embolization techniques and outcomes for pelvic AVMs, highlighting the need for standardized treatment strategies.

## Key findings

- Embolization therapy achieved high technical and clinical success rates in treating pelvic AVMs.
- Venous approaches, especially direct puncture of a dominant outflow vein, were most commonly used.
- Coils were the primary embolic agent, often combined with adjunctive materials.

## Abstract

A pelvic arteriovenous malformation (AVM) is a rare congenital vascular anomaly that may cause relevant clinical symptoms. This systematic review synthesizes current evidence on diagnostic approaches, embolization techniques, and clinical outcomes for pelvic AVMs. A PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses)-compliant literature search identified 19 studies comprising 49 patients treated with embolization therapy. Venous approaches, including direct puncture of a dominant outflow vein (DOV), were most commonly performed. Coils were the primary embolic agent, frequently combined with adjunctive materials, reflecting substantial technical heterogeneity. Despite this variability, embolization achieved consistently high technical and clinical success rates with low complication rates over a mean follow-up of 21.1 months. Embolization therapy of DOV may be considered as first-line therapy for symptomatic pelvic AVMs, although future comparative studies are needed to guide standardized treatment strategies.

## Full-text entities

- **Diseases:** thigh pain (MESH:D010146), retroperitoneal (MESH:D012186), hematuria (MESH:D006417), skin necrosis (MESH:D012871), injury (MESH:D014947), gastrointestinal symptoms (MESH:D012817), Complications (MESH:D008107), hemoperitoneum (MESH:D006465), hematoma (MESH:D006406), varicose veins (MESH:D014648), abdominal and/or pelvic pain (MESH:D015746), vascular abnormalities (MESH:D014652), fatigue (MESH:D005221), vascular malformations (MESH:D054079), arterio-venous malformation (MESH:D001159), febrile (MESH:D000071072), bleeding (MESH:D006470), Dysplastic (MESH:D004416), pulmonary vasospasm (MESH:D020301), PHIL (MESH:C000719195), ischemia (MESH:D007511), DOV (MESH:D014694), fever (MESH:D005334), bladder necrosis (MESH:D001745), pulmonary embolism (MESH:D011655), nerve injury (MESH:D000080902), pelvic pain (MESH:D017699), vaginal bleeding (MESH:D014592), paresis (MESH:D010291), vena cava (MESH:D013479), menorrhagia (MESH:D008595), Inferior (MESH:D056989), urinary symptoms (MESH:D059411), cardiovascular collapse (MESH:D002318), constipation (MESH:D003248), ovarian insufficiency (MESH:D010051), cardiac symptoms (MESH:D006331), embolization (MESH:D004617), uterine trauma (MESH:D014591), high-output cardiac failure (MESH:D006333), AVM (MESH:D001165), gastrointestinal bleeding (MESH:D006471), AVMs (MESH:C564254), congenital vascular anomaly (MESH:D020785), tissue necrosis (MESH:D009336)
- **Chemicals:** n-butyl cyanoacrylate (MESH:D004659), ethanol (MESH:D000431), DOV (-), polidocanol (MESH:D000077423)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12950127/full.md

## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12950127/full.md

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Source: https://tomesphere.com/paper/PMC12950127