# Percutaneous Transhepatic Variceal Embolization as a Therapeutic Bridge for Variceal Bleeding: An Initial Alternative in the Absence of Endoscopy or Transjugular Intrahepatic Portosystemic Shunt (TIPS)

**Authors:** Oscar F Vargas, Juliana Salcedo-Mesa, Laura Camila Ortiz Layton, William Alvarez

PMC · DOI: 10.7759/cureus.102492 · Cureus · 2026-01-28

## TL;DR

A new treatment called percutaneous transhepatic variceal embolization helps stop dangerous bleeding in cirrhosis patients when standard methods aren't available.

## Contribution

PTVE is proposed as a novel bridge therapy for variceal bleeding in resource-limited settings.

## Key findings

- PTVE achieved immediate hemostasis and hemodynamic stabilization in a cirrhosis patient.
- PTVE can serve as an alternative when endoscopy or TIPS are unavailable.
- The combined coil and Onyx strategy was effective in controlling variceal bleeding.

## Abstract

Variceal gastrointestinal bleeding in patients with liver cirrhosis is a potentially fatal complication that requires prompt hemostatic control. Standard management includes vasoactive therapy, antibiotic prophylaxis, and urgent endoscopic intervention, with transjugular intrahepatic portosystemic shunt reserved for selected high-risk or refractory cases. However, in resource-limited settings, timely access to endoscopy or definitive portal decompression may be delayed or unavailable, increasing the risk of hemodynamic deterioration and early mortality. We report the case of a 64-year-old woman with cirrhosis who developed hypovolemic shock secondary to gastroesophageal variceal hemorrhage and was treated with percutaneous transhepatic variceal embolization (PTVE) using a combined coil and ethylene-vinyl alcohol copolymer (Onyx) strategy, achieving immediate hemostasis and hemodynamic stabilization. This case highlights PTVE as a feasible bridge therapy in acute variceal bleeding when endoscopic or definitive portal decompression strategies are delayed or unavailable.

## Full-text entities

- **Genes:** ALB (albumin) [NCBI Gene 213] {aka FDAHT, HSA, PRO0883, PRO0903, PRO1341}
- **Diseases:** erythematous gastritis (MESH:D005756), pulmonary embolism (MESH:D011655), gastrointestinal bleeding (MESH:D006471), hemolysis (MESH:D006461), type 2 diabetes mellitus (MESH:D003924), embolization (MESH:D004617), hematemesis (MESH:D006396), esophageal or gastric varices (MESH:D004932), Bleeding (MESH:D006470), renal impairment (MESH:D007674), hypoalbuminemia (MESH:D034141), diabetic ketoacidosis (MESH:D016883), Cryptogenic cirrhosis (MESH:C562577), hepatic encephalopathy (MESH:D006501), coagulation (MESH:D001778), rupture (MESH:D012421), thrombocytopenia (MESH:D013921), cryptogenic liver cirrhosis (MESH:D008103), epigastric abdominal pain (MESH:D015746), ulcer (MESH:D014456), hemorrhagic shock (MESH:D012771), ascites (MESH:D001201), anemia (MESH:D000740), hypovolemic shock (MESH:D012769), Liver Diseases (MESH:D008107), portal hypertension (MESH:D006975), cirrhosis (MESH:D005355), Variceal upper gastrointestinal bleeding (MESH:D014648), thrombosis (MESH:D013927), critically ill (MESH:D016638), hypertensive (MESH:D006973), encephalopathy (MESH:D001927), death (MESH:D003643), cirrhotic (MESH:D000094724), antral (MESH:D020252), melena (MESH:D008551)
- **Chemicals:** creatinine (MESH:D003404), insulin (MESH:D007328), metformin (MESH:D008687), spironolactone (MESH:D013148), bilirubin (MESH:D001663), omeprazole (MESH:D009853), sitagliptin (MESH:D000068900), cyanoacrylate (MESH:D003487), propranolol (MESH:D011433), Axiostat (-), sodium (MESH:D012964), Onyx (MESH:C020320)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12949843/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12949843/full.md

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Source: https://tomesphere.com/paper/PMC12949843