# Sudden Cardiac Arrest After Endurance Cycling Due to Silent Three-Vessel Coronary Artery Disease: A Case Report

**Authors:** Resha R Ganthan, Rayna Isber, Joud Fahed, Asher Gorantla, Nidal Isber

PMC · DOI: 10.7759/cureus.102566 · Cureus · 2026-01-29

## TL;DR

A middle-aged cyclist suffered sudden cardiac arrest after a high-intensity event due to undetected severe coronary artery disease.

## Contribution

This case report highlights how asymptomatic CAD can be unmasked by endurance exercise, leading to life-threatening arrhythmias.

## Key findings

- High-intensity endurance exercise can reveal advanced, asymptomatic coronary artery disease in middle-aged athletes.
- Prompt CPR and defibrillation were critical in achieving return of spontaneous circulation after cardiac arrest.
- Successful treatment was achieved through coronary artery bypass grafting without the need for an implantable cardioverter-defibrillator.

## Abstract

Sudden cardiac arrest (SCA) during endurance exercise in middle-aged athletes is uncommon but is most frequently caused by occult coronary artery disease (CAD).

A 51-year-old, previously healthy, recreational cyclist collapsed immediately after completing a high-intensity 40-mile cycling event. He was found to be in ventricular fibrillation (VF) and achieved return of spontaneous circulation (ROSC) following prompt bystander cardiopulmonary resuscitation (CPR) and defibrillation. Initial electrocardiography and transthoracic echocardiography demonstrated no abnormalities and preserved left ventricular systolic function. Coronary angiography revealed severe three-vessel CAD, including critical proximal left anterior descending artery stenosis and chronic total occlusion of an obtuse marginal branch. The patient underwent successful coronary artery bypass grafting (CABG). Given the preserved ventricular function and a reversible ischemic cause, implantable cardioverter-defibrillator (ICD) implantation was not indicated.

This case highlights the ability of high-intensity endurance exercise to unmask advanced, asymptomatic CAD and precipitate malignant ventricular arrhythmias in middle-aged athletes, emphasizing the importance of individualized cardiovascular risk assessment and emergency preparedness at endurance events.

## Linked entities

- **Diseases:** sudden cardiac arrest (MONDO:0100511), coronary artery disease (MONDO:0005010), ventricular fibrillation (MONDO:0000190)

## Full-text entities

- **Diseases:** hyperlipidemia (MESH:D006949), diabetes (MESH:D003920), ischemic (MESH:D002545), three-vessel (MESH:C536223), malignant (MESH:D009369), cardiac arrest (MESH:D006323), ventricular arrhythmias (MESH:D001145), chest pain (MESH:D002637), stroke (MESH:D020521), SCA (MESH:D016757), ischemia (MESH:D007511), stenoses (MESH:D003251), arrhythmic (OMIM:212500), thrombosis (MESH:D013927), obstructive disease (MESH:D001157), hypertension (MESH:D006973), death (MESH:D003643), atherosclerotic disease (MESH:D050197), left anterior descending artery stenosis (MESH:D012078), Event (MESH:D002318), ischemic myocardial injury (MESH:D017202), dizziness (MESH:D004244), heart failure (MESH:D006333), renal dysfunction (MESH:D007674), CAD (MESH:D003324), heart disease (MESH:D006331), VF (MESH:D014693), coronary calcification (MESH:D003323)
- **Chemicals:** oxygen (MESH:D010100), aspirin (MESH:D001241), implantable (-), clopidogrel (MESH:D000077144), catecholamine (MESH:D002395), calcium (MESH:D002118)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12949620/full.md

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Source: https://tomesphere.com/paper/PMC12949620