# A Rare Infectious Complication Following Transrectal Prostate Biopsy: Spondylodiscitis With Contiguous Psoas Muscle Abscess

**Authors:** Luis Carlos, Ronaldo Mayta, Mijail Vega, Diego Salazar, Andrea Sanchez

PMC · DOI: 10.7759/cureus.102560 · Cureus · 2026-01-29

## TL;DR

A rare spinal infection with a psoas abscess occurred after a prostate biopsy, highlighting the importance of early diagnosis and MRI for effective treatment.

## Contribution

This case highlights the rare but serious complication of spondylodiscitis following transrectal prostate biopsy and emphasizes the role of MRI in diagnosis.

## Key findings

- Spondylodiscitis with psoas abscess occurred 24 hours after a transrectal prostate biopsy.
- MRI was crucial for diagnosing the infection and guiding treatment.
- Empirical antibiotics were adjusted after E. coli was identified from cultures.

## Abstract

Spondylodiscitis is a rare but potentially serious spinal infection. Although Staphylococcus aureus is the most common pathogen, Escherichia coli has been increasingly associated with genitourinary procedures such as transrectal prostate biopsy, even with antibiotic prophylaxis.

We present the case of a 71-year-old man who underwent a transrectal prostate biopsy due to elevated prostate-specific antigen (PSA) levels. He developed fever and lower back pain 24 hours after the procedure. Initial studies suggested a bacterial infection, and empirical antibiotic treatment was initiated. Lumbar magnetic resonance imaging (MRI) revealed L4-L5 spondylodiscitis with left paravertebral involvement and an ipsilateral psoas abscess. Computed tomography (CT)-guided percutaneous drainage and disc biopsy were performed. Cultures isolated E. coli, allowing for adjustment of the antibiotic treatment, with a favorable clinical outcome.

Although spondylodiscitis secondary to transrectal prostate biopsy is uncommon, the presence of fever and lower back pain was key to the diagnostic suspicion. Imaging studies, particularly MRI, proved essential for establishing the diagnosis and guiding effective treatment.

Infectious spondylodiscitis is a rare but potentially fatal complication following transrectal prostate biopsy. Early clinical suspicion and prompt pathogen identification are essential. MRI and image-guided minimally invasive procedures, including percutaneous biopsy and drainage, play a key role in diagnosis and effective management.

## Linked entities

- **Diseases:** bacterial infection (MONDO:0005113)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, KLK3 (kallikrein related peptidase 3) [NCBI Gene 354] {aka APS, KLK2A1, PSA, hK3}
- **Diseases:** urinary retention (MESH:D016055), neutrophilia (MESH:C563010), back pain (MESH:D001416), intervertebral (MESH:C535531), anemia (MESH:D000740), leukocytosis (MESH:D007964), bone destruction (MESH:D001847), erosions (MESH:D014077), osteolysis (MESH:D010014), urinary tract infections (MESH:D014552), thrombocytopenia (MESH:D013921), spondylitis (MESH:D013166), chills (MESH:D023341), LUTS (MESH:D059411), Infection (MESH:D007239), vertebral osteomyelitis (MESH:D010019), osteochondrosis (MESH:D055034), bacterial infection (MESH:D001424), Infectious (MESH:D003141), necrosis (MESH:D009336), hematuria (MESH:D006417), prostate cancer (MESH:D011471), abscess (MESH:D000038), inflammation (MESH:D007249), bone edema (MESH:D004487), Spondylodiscitis (MESH:D015299), rectal bleeding (MESH:D012002), spondylosis (MESH:D055009), lymphopenia (MESH:D008231), malignancy (MESH:D009369), psoas abscess (MESH:D016659), spinal syndrome (MESH:D020759), hemorrhage (MESH:D006470), sclerosis (MESH:D012598), lower back pain (MESH:D017116), fever (MESH:D005334), neurological compromise (MESH:D009461), HCM (MESH:D000092183)
- **Chemicals:** hematoxylin (MESH:D006416), fluoroquinolone (MESH:D024841), trimethoprim-sulfamethoxazole (MESH:D015662), Imipenem (MESH:D015378), eosin (MESH:D004801), beta-lactams (MESH:D047090), tamsulosin (MESH:D000077409), metronidazole (MESH:D008795), ciprofloxacin (MESH:D002939), amoxicillin-clavulanic acid (MESH:D019980), carbapenems (MESH:D015780)
- **Species:** Homo sapiens (human, species) [taxon 9606], Staphylococcus aureus (species) [taxon 1280], Escherichia coli (E. coli, species) [taxon 562]

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12949602/full.md

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Source: https://tomesphere.com/paper/PMC12949602