# Drinking motives among patients with alcohol use disorder: a longitudinal study

**Authors:** Lars Sjödin, Olof Molander, Stina Ingesson-Hammarberg, Anders Hammarberg

PMC · DOI: 10.1186/s13722-026-00656-4 · Addiction Science & Clinical Practice · 2026-02-26

## TL;DR

This study tracked drinking motives in patients with alcohol use disorder over two years and found that changes in these motives were linked to reductions in alcohol-related problems.

## Contribution

The study provides longitudinal evidence on how drinking motives influence alcohol use disorder severity in clinical populations.

## Key findings

- Reductions in drinking motives and alcohol-related outcomes were observed over two years.
- Enhancement motives were most prevalent and linked to reduced AUD severity over time.
- Higher baseline enhancement motives predicted greater reductions in alcohol problems.

## Abstract

This current two-year clinical study among adult patients with alcohol use disorder (AUD) examined drinking motives and their cross-sectional and longitudinal associations with alcohol consumption, severity of AUD, and other alcohol-related problems. Enhancement, coping, conformity, and social motives have been found to impact alcohol use, yet longitudinal studies on drinking motives in clinical populations are sparse.

This observational study used data from a randomized controlled trial (RCT) conducted in Stockholm, Sweden, from 2017 to 2022, including 250 participants with AUD. Data from both treatment groups were included. Assessments of study outcomes were conducted at five time points: at baseline, and after 12, 26, 52, and 104 weeks. Self-report questionnaires and diagnostic interviews were used to assess drinking motives, alcohol consumption, alcohol-related problems, and mental health. Instruments used for self-reports included: The Drinking Motives Questionnaire-Revised Short Form (DMQ-R SF) and the Alcohol Use Disorders Identification Test (AUDIT). The DMQ-R SF assessed enhancement, coping, conformity, and social motives. The AUDIT assessed self-perceived alcohol problems. Interviews were conducted to assess alcohol consumption using the Timeline Follow-Back method (TLFB) and AUD using the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Generalized linear models were used to examine associations between drinking motives (DMQ R-SF) and alcohol-related outcomes (TLFB/AUDIT/AUD by the DSM-5).

Reductions in both drinking motives (enhancement 15.6%, coping 23.6%, conformity 15.4%, and social 17.9%) and alcohol-related outcomes (drinks per week 40.5%, number of DSM-5 criteria 50.9%, and AUDIT total score 36.3%) were observed during the study period. Across outcomes, the most prevalent drinking motives was enhancement, followed by social, coping, and conformity motives. Elevated enhancement, coping and social motives were cross-sectionally associated with worse alcohol-related outcomes at different time points, whereas higher conformity motives had links to less alcohol consumption. Higher enhancement motives at baseline predicted a larger reduction in the severity of alcohol problems from baseline to the 104-week follow-up.

Enhancement motives were most prevalent among people with AUD, and higher enhancement motives were associated with reductions in AUD severity over time. Motive domains likely play a role in understanding changes in the severity of AUD over time.

The original RCT study was registered retrospectively at isrctn.com (14539251), registration date 04/09/2018.

The online version contains supplementary material available at 10.1186/s13722-026-00656-4.

## Full-text entities

- **Genes:** SLTM (SAFB like transcription modulator) [NCBI Gene 79811] {aka Met}, GPT (glutamic--pyruvic transaminase) [NCBI Gene 2875] {aka AAT1, ALT, ALT1, GPT1, SGPT}, GGT1 (gamma-glutamyltransferase 1) [NCBI Gene 2678] {aka CD224, D22S672, D22S732, GGT, GGT 1, GGTD}, GGTLC5P (gamma-glutamyltransferase light chain 5 pseudogene) [NCBI Gene 653590] {aka GGT}, SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}
- **Diseases:** -5 (MESH:D008232), Depression (MESH:D003866), Dependency Disorders (MESH:D003859), BSCT (MESH:D012652), drunkenness (MESH:D000435), bipolar disorder (MESH:D001714), alcohol problems (MESH:D019973), major depression (MESH:D003865), MI (MESH:D003072), nicotine use disorder (MESH:D014029), drinking problems (MESH:D063425), AUD (MESH:D000437), Generalized Anxiety Disorder (MESH:C000726808), COVID-19 (MESH:D000086382), Mental Disorders (MESH:D001523), dependence (MESH:D019966), Anxiety (MESH:D001007)
- **Chemicals:** Alcohol (MESH:D000438), ethanol (MESH:D000431), BSCT (-)
- **Species:** Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]

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## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12949512/full.md

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Source: https://tomesphere.com/paper/PMC12949512