# Association of Physical Activity and Socioeconomic Status With Glycaemic Control in Adults With Type 1 Diabetes: A Cross‐Sectional Study Using CGM Data

**Authors:** Fernando Sebastian‐Valles, Rafael Simó, Jose Alfonso Arranz Martín, Mercè Abad, Alicia Justel Enriquez, Cristina Pérez‐Fernández, Sara Jiménez Blanco, Cristina Hernández, Mónica Marazuela, Olga Simó‐Servat

PMC · DOI: 10.1002/dmrr.70146 · Diabetes/Metabolism Research and Reviews · 2026-02-27

## TL;DR

This study finds that physical activity improves blood sugar control in adults with type 1 diabetes, regardless of income level.

## Contribution

The study shows physical activity partially mediates the effect of income on glycaemic control in type 1 diabetes patients.

## Key findings

- Higher physical activity and income are independently linked to better glycaemic control.
- Physical activity partially mediates income's effect on time in range (TIR) by 23%.
- Active individuals have 16% lower insulin needs and better lipid profiles, independent of income.

## Abstract

This study examined the independent and combined effects of physical activity and socioeconomic status (SES) on glycaemic control in adults with T1D using continuous glucose monitoring (CGM).

A cross‐sectional study included 423 adults with T1D from a public healthcare setting in whom physical activity was self‐assessed via the short‐form International Physical Activity Questionnaire (IPAQ). SES was estimated using mean annual net income by census tract. Glycaemic outcomes included time in range (TIR) and time in tight range (TITR), derived from CGM, and HbA1c. Multivariable linear models and four‐way mediation analyses were conducted.

Higher physical activity and income were independently associated with better glycaemic control. The highest activity quartile was associated with +8.0% TIR and −0.47% HbA1c (p < 0.01). Physical activity partially mediated the effect of income on TIR (pure indirect effect β = 2.42, p = 0.013), accounting for 23% of the total effect. No significant SES–activity interaction was observed. Physically active individuals also had a 16% lower insulin requirement and better lipid profile, independent of income. A modest TBR increase occurred without longer hypoglycaemia.

Physical activity is associated with improved glycaemic and lipid control in T1D patients, regardless of income. Promoting physical activity might reduce SES‐related glycaemic disparities and improve outcomes.

## Linked entities

- **Diseases:** Type 1 Diabetes (MONDO:0005147)

## Full-text entities

- **Genes:** INS (insulin) [NCBI Gene 3630] {aka IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10}
- **Diseases:** hypertension (MESH:D006973), cardiovascular and microvascular complications (MESH:D002318), diabetic polyneuropathy (MESH:D003929), ischaemic stroke (MESH:D002544), nephropathy (MESH:D007674), TIR (MESH:D000377), ischaemic heart disease (MESH:D006331), T1D (MESH:D003922), diabetic nephropathy (MESH:D003928), foot disease (MESH:D005534), mitochondrial dysfunction (MESH:D028361), polyneuropathy (MESH:D011115), Diabetes (MESH:D003920), retinopathy (MESH:D058437)
- **Chemicals:** Remnant (-), carbohydrate (MESH:D002241), Lipid (MESH:D008055), alcohol (MESH:D000438), Glucose (MESH:D005947), triglycerides (MESH:D014280), Cholesterol (MESH:D002784), insulin (MESH:D007328)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12949369/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12949369/full.md

## References

46 references — full list in the complete paper: https://tomesphere.com/paper/PMC12949369/full.md

---
Source: https://tomesphere.com/paper/PMC12949369