# Medial Patellofemoral Ligament Reconstruction vs Nonoperative Treatment for Recurrent Lateral Patellar Dislocation: Three-Year Results From a Randomized Controlled Trial

**Authors:** Truls Martin Straume-Næsheim, Per-Henrik Randsborg, Tina Løkken Nilsgård, Asbjørn Årøen

PMC · DOI: 10.1177/03635465261416931 · The American Journal of Sports Medicine · 2026-02-08

## TL;DR

This study found that surgery to reconstruct the medial patellofemoral ligament is more effective than non-surgical treatment in preventing repeated patellar dislocations over three years.

## Contribution

The study provides three-year clinical evidence comparing MPFL-R to nonoperative treatment in patients without anatomic risk factors for recurrent patellar dislocation.

## Key findings

- MPFL-R reduced patellar instability recurrence to 16.7% compared to 53.6% in the control group.
- Both groups showed significant improvement in knee function over three years.
- No significant differences in patient-reported outcome scores were found between the groups.

## Abstract

Medial patellofemoral ligament reconstruction (MPFL-R) is the primary surgical intervention for recurrent lateral patellar dislocation (LPD). Isolated MPFL-R is recommended for patients without anatomic high-risk factors that predispose to further dislocations.

To compare instability recurrence in patients with recurrent LPD without underlying anatomic risk factors treated with MPFL-R versus active rehabilitation.

Randomized controlled clinical trial; Level of evidence, 1.

Patients aged 12 to 30 years with recurrent LPD and no underlying anatomic high-risk factors for further dislocations—specifically, no severe trochlear dysplasia (Dejour D) and a tibial tuberosity–trochlear groove distance ≤20 mm on computed tomography—were randomized to receive knee arthroscopy with isolated MPFL-R followed by active rehabilitation (MPFL group) or knee arthroscopy without reconstruction followed by active rehabilitation (control group). The primary outcome was subjective persistent patellar instability at 3 years. Knee function at baseline and 1 and 3 years was assessed by the following patient-reported outcome measure (PROM) scores: Knee injury and Osteoarthritis Outcome Score (KOOS), Kujala Knee Score, Cincinnati Knee Rating System, and Noyes Sports Activity Rating Scale.

Between 2010 and 2019, 61 patients (72.1% female) were included in the study and randomized, with 30 assigned to the MPFL group and 31 to the control group. At 3-year follow-up, subjective persistent patellar instability was reported by 5 patients in the MPFL group (16.7%) versus 15 patients in the control group (53.6%), corresponding to an odds ratio of 5.8 (95% CI, 1.7-19.4; P = .003). Both groups reported significant improvements in all PROM scores from baseline to 3 years. However, no significant differences in PROM scores were observed between the groups at any follow-up time point.

Isolated MPFL-R was more effective than active rehabilitation alone in preventing patellar instability after 3 years.

ClinicalTrials.org (NCT02263807).

## Full-text entities

- **Genes:** MSLNL (mesothelin like) [NCBI Gene 401827] {aka C16orf37, MPFL}
- **Diseases:** trochlear dysplasia (MESH:D020432), Dejour D (MESH:D014808), Osteoarthritis (MESH:D010003), LPD (MESH:D031222), Knee injury (MESH:D007718), dislocations (MESH:D004204)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12949040/full.md

## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC12949040/full.md

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Source: https://tomesphere.com/paper/PMC12949040