# Normative data for interorbital distance in a paediatric Caucasian population

**Authors:** Mathilde Pech de Laclause, Baptiste Morel, Boris Laure, Anne Morice

PMC · DOI: 10.1007/s00276-026-03849-3 · Surgical and Radiologic Anatomy · 2026-02-27

## TL;DR

This study provides normative data on orbital growth in Caucasian children, identifying key developmental periods.

## Contribution

The study establishes detailed normative data for interorbital distance in a healthy Caucasian pediatric population.

## Key findings

- Interorbital distance increases progressively from 3 months to 10 years of age.
- Significant growth spurts occur between 0-2 years and 7-8 years.
- The IOD/LOD ratio remains constant, indicating isometric orbital growth.

## Abstract

Orbital growth represents a key component of craniofacial development to investigate due to the many craniofacial abnormalities which can interfere with it. Defining orbital growth patterns is essential for distinguishing physiological from pathological orbital development. Normative orbital growth data in Caucasian paediatric populations remain scarce.

Our study aimed to determine interorbital distance in a healthy Caucasian children population.

A retrospective study was conducted in France, based on craniofacial CT scans measurements in patients aged from 3 months to 10 years. Measurements were taken at the neuro-ocular plane and included the bony inner interorbital distance (IOD), bony lateral orbital distance (LOD), and IOD/LOD ratio. Mean +/- SD was calculated for each age group, and comparisons between sexes and age groups were performed using the Mann–Whitney test (p < 0.05).

A total of 466 CT-scans were analysed (216 females and 250 males). The mean IOD increased progressively, from 18.76 +/- 1.17 mm at 3 months to 22.79 +/- 1.73 mm at 10 years of age. The most important increase of IOD and LOD values was observed during the first 2 years of age (p < 0.01) and between 7 and 8 years of age (p < 0.05). The IOD/LOD ratio remained constant with age, showing isometric growth of the orbits.

This study provides detailed normative data of orbital measurements in Caucasian children and highlights two critical periods of accelerated orbital growth.

The online version contains supplementary material available at 10.1007/s00276-026-03849-3.

## Full-text entities

- **Diseases:** encephaloceles (MESH:D004677), infectious (MESH:D003141), plagiocephaly (MESH:D059041), facial fracture (MESH:D005153), Orbital Distance (MESH:D009916), Hypertelorism (MESH:D006972), craniofacial abnormalities (MESH:D019465), craniofacial clefts (MESH:D005157), craniofacial syndrome (MESH:C565118), Trigonocephaly (MESH:D003398), craniofrontonasal dysplasia (MESH:C536456), Williams syndrome (MESH:D018980), trisomy 13 (MESH:D000073839), Meckel-Gruber syndrome (MESH:C536133), congenital and tumoral craniofacial diseases (MESH:D009369), holoprosencephaly (MESH:D016142), syndromic anomalies (MESH:D000013), Coffin-Siris syndrome (MESH:C536436), Hypotelorism (MESH:C563509), headaches (MESH:D006261), IOD (MESH:C535290), head trauma (MESH:D006259)
- **Chemicals:** dacryon (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12948904/full.md

## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12948904/full.md

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Source: https://tomesphere.com/paper/PMC12948904