# Ruptured Sinus of Valsalva Aneurysm With 2 Simultaneous Fistulas to the Left Ventricular Outflow Tract

**Authors:** Ryoto Mitsumizo, Ryuichi Matsukawa, Takayuki Uchida, Jun-ichiro Nishi

PMC · DOI: 10.1016/j.jaccas.2025.106612 · JACC Case Reports · 2026-01-21

## TL;DR

A rare case of a ruptured heart aneurysm with two fistulas to the left ventricle is reported, showing successful delayed surgical repair.

## Contribution

This is the first reported case of a noncoronary cusp SOVA rupturing into two left ventricular outflow tract fistulas.

## Key findings

- The patient remained asymptomatic with stable hemodynamics, allowing elective surgical repair.
- The left-to-left shunt decompressed the aneurysmal sac, preventing acute heart failure.
- Histopathological findings suggested age-related degeneration as the cause.

## Abstract

Sinus of Valsalva aneurysm (SOVA) rupture usually forms fistulas into right heart chambers; left-sided ruptures are exceedingly rare.

A 73-year-old woman presented for evaluation of ST-segment depression in V5 and V6 and moderate aortic regurgitation. Imaging revealed a noncoronary cusp–origin SOVA with 2 simultaneous fistulas into the left ventricular outflow tract. She remained asymptomatic with stable hemodynamics, allowing elective surgical repair with patch closure, direct suture, and bioprosthetic valve replacement.

The left-to-left shunt decompressed the aneurysmal sac, preventing acute heart failure. Unlike typical left-to-right ruptures, these favorable flow dynamics allowed safe delayed intervention. Histopathological examination suggested age-related degeneration rather than congenital or inflammatory etiology.

This is the first reported case of a noncoronary cusp SOVA rupturing into 2 left ventricular outflow tract fistulas. Careful hemodynamic assessment is crucial, as select patients may benefit from elective rather than urgent repair.

## Full-text entities

- **Diseases:** SOVA (MESH:D000783), left ventricular outflow tract fistulas (MESH:D000092242), ST-segment depression (MESH:D000072657), Fistulas (MESH:D005402), aortic regurgitation (MESH:D001022), ruptures (MESH:D012421), inflammatory (MESH:D007249), heart failure (MESH:D006333)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12948572/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12948572/full.md

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Source: https://tomesphere.com/paper/PMC12948572