This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTION: Involvement of Heme Oxygenase‐1 Participates in Anti‐Inflammatory and Analgesic Effects of Aqueous Extract of Hibiscus taiwanensis
Evidence-Based Complementary and Alternative Medicine

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsHibiscus Plant Research Studies · Plant-based Medicinal Research · Natural Antidiabetic Agents Studies
RETRACTION: S.‐L. Liu, J.‐S. Deng, C.‐S. Chiu, et al., “Involvement of Heme Oxygenase‐1 Participates in Anti‐Inflammatory and Analgesic Effects of Aqueous Extract of Hibiscus taiwanensis,” Evidence-Based Complementary and Alternative Medicine, vol. 2012 (2012). https://doi.org/10.1155/2012/132859.
The above article, published online on 21 June 2012 in Wiley Online Library (https://wileyonlinelibrary.com), has been retracted by John Wiley & Sons Ltd.
The retraction has been agreed following an investigation of the concerns raised by Actinopolyspora biskrensis on PubPeer [1], which identified several concerns related to multiple figures in the paper. More specifically,
Figure 5a: The COX‐2 and B‐Actin bands are identical after a horizontal stretch.
Figure 6a: The image of the control and Carr panels shares overlapping features with Figure 8a of [2] and 4a of [3].
As a result of the investigation, the data and conclusions of this article are considered unreliable.
The authors have been informed of this decision but did not provide a response.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Actinopolyspora biskrensis, “Involvement of Heme Oxygenase-1 Participates in Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Hibiscus taiwanensis,” Pub Peer, June 2024. https://pubpeer.com/publications/010D 5B 150AD 6ABE 3F 887569 E 0CFB 55.10.1155/2012/132859 PMC 338851922778769 · doi ↗ · pubmed ↗
- 2Liao J.-C. , Deng J.-S. , Chiu C.-S. et al., Anti-Inflammatory Activities of Cinnamomum cassia Constituents In Vitro and In Vivo , Evidence-Based Complementary and Alternative Medicine. (2012) 2012, 10.1155/2012/429320, 2-s 2.0-84859763499.PMC 331890522536283 · doi ↗ · pubmed ↗
- 3Chang T.-N. , Deng J.-S. , Chang Y.-C. et al., Ameliorative Effects of Scopoletin from Crossostephium chinensis against Inflammation Pain and Its Mechanisms in Mice, Evidence-Based Complementary and Alternative Medicine. (2012) 2012, 10.1155/2012/595603, 2-s 2.0-84867019397.PMC 344358022991572 · doi ↗ · pubmed ↗
