# Ethnopharmocological study of medicinal plants used for treatment of skin diseases by herbalists in Northwestern region of Algeria

**Authors:** Razika Hantour, Yasmina Benabdesslem, Mustapha Diaf, Kadda Hachem, Samia Ghomari

PMC · DOI: 10.1371/journal.pone.0343714 · PLOS One · 2026-02-27

## TL;DR

This study explores traditional herbal treatments for skin diseases in Northwestern Algeria, documenting 73 plant species used by herbalists.

## Contribution

The study provides a detailed ethnopharmacological analysis of plant-based treatments for skin ailments in a specific Algerian region.

## Key findings

- 73 plant species from 29 families were reported for treating skin ailments, with Lamiaceae and Asteraceae being the most common.
- Allium sativum and Thymus vulgaris were the most frequently cited plants based on RFC values.
- Leaves were the most commonly used plant part, and topical application was the primary mode of administration.

## Abstract

Skin disease is a major public health concern worldwide, particularly in developing countries. Despite the rich diversity of medicinal plants and strong traditional healing practices in Algeria, the dependence on imported pharmaceuticals remains high. This study documents and analyzes traditional herbal knowledge related to the treatment of skin diseases in Northwestern Algeria (Mascara, Saïda, and Sidi Bel Abbès) with the aim to preserve and scientifically validate this ethnomedicinal heritage.

A total of 117 herbalists (110 men and seven women) were interviewed using semi-structured questionnaires between September 2023 and July 2024. Data were analyzed using quantitative ethnobotanical indices, including the Relative Frequency of Citations (RFC) and Plant Part Value (PPV), to assess the cultural significance and usage frequency of medicinal species.

A total of 73 plant species belonging to 29 families have been reported for the treatment of various skin ailments. The most abundant families were Lamiaceae, Asteraceae, Cucurbitaceae, Liliaceae, Cupressaceae, and Fabaceae. Allium sativum L. and Thymus vulgaris L. showed the highest RFC values (0.175 and 0.124, respectively). Leaves were the most frequently used plant parts (PPV = 0.48; 47.6%), followed by fruits (PPV = 0.12; 11.6%), and seeds (PPV = 0.09; 8.9%). Most of the remedies were prepared from dried plants (65.31%), powders (39.9%), and decoctions (22.55%) being the main preparation methods. Topical application (35.2%), poultices (30%), and rinsing (25%) were the most common modes of administration. The most frequently treated skin conditions were eczema, psoriasis, and acne.

This study highlights the remarkable ethnopharmacological knowledge preserved among herbalists in Northwestern Algeria, including women’s traditional roles in medicinal practices. The documentation of these findings not only assists preserve valuable cultural heritage but also provides a foundation for future pharmacological research and the sustainable use of the rich medicinal flora of Algeria.

## Linked entities

- **Diseases:** eczema (MONDO:0004980), psoriasis (MONDO:0005083), acne (MONDO:0011438)

## Full-text entities

- **Diseases:** depression (MESH:D003866), contact dermatitis (MESH:D003877), allergies (MESH:D004342), insect bites (MESH:D007299), cutaneous mycoses (MESH:D009181), acne (MESH:D000152), atopic dermatitis (MESH:D003876), inflammatory, autoimmune, congenital, chronic, and neoplastic diseases (MESH:D019693), cutaneous leishmaniasis (MESH:D016773), corns (MESH:D002145), infectious (MESH:D003141), arthritis (MESH:D001168), Eczema (MESH:D004485), skin infections (MESH:D007239), cardiovascular disease (MESH:D002318), gastrointestinal complications (MESH:D005767), scabies (MESH:D012532), toxic (MESH:D064420), dermatological conditions (MESH:D000168), ulcers (MESH:D014456), autoimmune conditions (MESH:D001327), alopecia (MESH:D000505), obesity (MESH:D009765), urticaria (MESH:D014581), skin cancer (MESH:D012878), dermatitis (MESH:D003872), cardiotoxicity (MESH:D066126), psoriasis (MESH:D011565), dermatophyte infections (MESH:D003881), pruritus (MESH:D011537), burns (MESH:D002056), herpes wounds (MESH:D014947), inflammation (MESH:D007249), warts (MESH:D014860), dermatoses (MESH:D012871), neurotoxicity (MESH:D020258), malignant (MESH:D009369), diaper dermatitis (MESH:C536239)
- **Chemicals:** polyphenols (MESH:D059808), allicin (MESH:C006452), coumarins (MESH:D003374), diterpenoids (MESH:D004224), flavonoids (MESH:D005419), RFC (-), olive oil (MESH:D000069463), carvacrol (MESH:C073316), Ajoenes (MESH:C048980), alliins (MESH:C006453), triterpenoids (MESH:D014315), tannins (MESH:D013634), water (MESH:D014867), aromatic alcohols (MESH:D019905), essential oils (MESH:D009822), terpenes (MESH:D013729), thymol (MESH:D013943), fat (MESH:D005223), Sugar (MESH:D000073893), sulfides (MESH:D013440)
- **Species:** Curcuma longa (turmeric, species) [taxon 136217], Citrullus colocynthis (alhandal, species) [taxon 252529], Nigella damascena (jack-in-the-green, species) [taxon 3444], Origanum vulgare (oregano, species) [taxon 39352], Lepidium sativum (species) [taxon 33125], Human alphaherpesvirus 2 (no rank) [taxon 10310], Dracocephalum officinale (hyssop, species) [taxon 39324], Homo sapiens (human, species) [taxon 9606], Ocimum basilicum (basil, species) [taxon 39350], Nerium oleander (common oleander, species) [taxon 63479], Salvia rosmarinus (rosemary, species) [taxon 39367], Allium sativum (garlic, species) [taxon 4682], Peganum harmala (species) [taxon 43879], Human alphaherpesvirus 1 (Herpes simplex virus type 1, no rank) [taxon 10298], Juniperus communis (common juniper, species) [taxon 58039], Candida albicans (species) [taxon 5476], Artemisia herba-alba (white wormwood, species) [taxon 72329], Pinus halepensis (Aleppo pine, species) [taxon 71633], Thymus vulgaris (common thyme, species) [taxon 49992], Juniperus oxycedrus (prickly juniper, species) [taxon 69008], Saccharomyces cerevisiae (baker's yeast, species) [taxon 4932], Trigonella foenum-graecum (fenugreek, species) [taxon 78534]

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## References

76 references — full list in the complete paper: https://tomesphere.com/paper/PMC12948081/full.md

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Source: https://tomesphere.com/paper/PMC12948081