# Better, not just fewer: Rethinking antibiotic prescribing

**Authors:** Giorgia Sulis, Derek R. MacFadden

PMC · DOI: 10.1371/journal.pmed.1004941 · PLOS Medicine · 2026-02-27

## TL;DR

This paper discusses how improving antibiotic prescriptions, not just reducing them, is crucial to combat antimicrobial resistance.

## Contribution

The paper introduces a new perspective on antibiotic prescribing that emphasizes quality over quantity.

## Key findings

- Clinical decision support tools alone are insufficient to address antimicrobial resistance.
- Behavioral, equity, and governance challenges must be addressed alongside technological solutions.
- Better prescriptions are essential for effective antimicrobial stewardship.

## Abstract

Clinical decision support tools can curb unnecessary antibiotic use, but success depends on more than technology. Here, we explore behavioral, equity, and governance challenges in tackling antimicrobial resistance, and why “better, not just fewer” prescriptions are essential.

Clinical decision support tools can curb unnecessary antibiotic use, but success depends on more than technology. In this Perspective, Giorgia Sulis and Derek MacFadden explore behavioral, equity, and governance challenges in tackling antimicrobial resistance, and why “better, not just fewer” prescriptions are essential.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** infection (MESH:D007239), deaths (MESH:D003643), infectious disease (MESH:D003141), malaria (MESH:D008288), AMR (MESH:D060467), acute illness (MESH:D000208), fatigue (MESH:D005221)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12948075/full.md

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Source: https://tomesphere.com/paper/PMC12948075