# Descending Colon Epiploic Appendagitis Mimicking Diverticulitis: A Case Report

**Authors:** Anas E Ahmed, Omar G Alahmadi, Abdullah H Althurwi, Osaid H Niazi, Yazen A Alomary

PMC · DOI: 10.7759/cureus.102484 · Cureus · 2026-01-28

## TL;DR

A 46-year-old man's abdominal pain was caused by epiploic appendagitis, not diverticulitis, showing the importance of accurate diagnosis to avoid unnecessary treatments.

## Contribution

This case report adds to the understanding of epiploic appendagitis as a rare but treatable cause of acute abdominal pain.

## Key findings

- CT imaging confirmed epiploic appendagitis with a fat-density lesion near the descending colon.
- Conservative treatment led to rapid symptom resolution and full recovery within two weeks.
- The case emphasizes the need to consider this condition in the differential diagnosis of acute abdominal pain.

## Abstract

Epiploic appendagitis is a rare, self-limiting cause of acute abdominal pain that often mimics more common conditions, such as diverticulitis, leading to frequent misdiagnosis and unnecessary interventions. We report a case of a 46-year-old male who presented with sudden-onset, sharp, localized left lower quadrant pain without systemic symptoms. Physical examination revealed localized tenderness without peritoneal signs, and laboratory tests showed only mild leukocytosis and slight elevation of inflammatory markers. Contrast-enhanced computed tomography demonstrated an oval, fat-density lesion adjacent to the descending colon with a hyperattenuating rim and surrounding fat stranding, consistent with epiploic appendagitis. The patient was managed conservatively with analgesia and supportive care, with rapid symptom resolution within 48 h and complete recovery at two-week follow-up. This case highlights the importance of considering epiploic appendagitis in the differential diagnosis of acute abdominal pain, particularly when systemic signs are minimal, and demonstrates the value of imaging in establishing a definitive diagnosis. Prompt recognition can prevent unnecessary antibiotics, hospitalization, or surgical intervention, allowing for safe and effective conservative management.

## Linked entities

- **Diseases:** diverticulitis (MONDO:0004235)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** Diverticulitis (MESH:D004238), abdominal pain (MESH:D015746), diverticular inflammation (MESH:D007249), abscess (MESH:D000038), left lower quadrant pain (MESH:D010146), diverticula (MESH:D004240), acute epiploic appendagitis (MESH:D000208), fever (MESH:D005334), omental (MESH:D015436), ischemia (MESH:D007511), vomiting (MESH:D014839), nausea (MESH:D009325), diarrhea (MESH:D003967), chills (MESH:D023341), peritonitis (MESH:D010538), gastrointestinal disorders (MESH:D005767), infection (MESH:D007239), urinary symptoms (MESH:D059411), leukocytosis (MESH:D007964), thrombosis (MESH:D013927), appendicitis (MESH:D001064), neutrophilia (MESH:C563010), melena (MESH:D008551), colorectal cancer (MESH:D015179), panniculitis (MESH:D015434), hypertension (MESH:D006973), necrosis (MESH:D009336), Epiploic Appendagitis (MESH:D018280), rigidity (MESH:D009127), intra-abdominal malignancy (MESH:D000082122), hematochezia (MESH:D006471), ischemic colitis (MESH:D017091), inflammatory bowel disease (MESH:D015212), infarction (MESH:D007238), constipation (MESH:D003248), costovertebral angle tenderness (MESH:D063806)
- **Chemicals:** oxygen (MESH:D010100), alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12947959/full.md

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Source: https://tomesphere.com/paper/PMC12947959