# Innovative HIV care strategies and health system resilience in conflict-affected settings

**Authors:** Swase Dominic Terkimbi, Patrick Maduabuchi Aja, Joseph Kibirige, Buyinza Nicholas, Ejike Daniel Eze, Afodun Adam Moyosore, Nancy Bonareri Mitaki, Elna Owembabazi, Samiah Shahid, Regan Mujinya

PMC · DOI: 10.1186/s13031-026-00757-6 · Conflict and Health · 2026-01-30

## TL;DR

This paper explores how to maintain HIV care in conflict zones by using innovative strategies and improving health system resilience.

## Contribution

The study introduces adaptive HIV care models and emphasizes the integration of mental health in conflict-affected regions.

## Key findings

- Governance collapse and ART stockouts undermine HIV care continuity in conflict zones.
- Differentiated service delivery and mobile clinics effectively sustain HIV care in fragile environments.
- Integrating mental health into HIV programs improves treatment outcomes in conflict settings.

## Abstract

Armed conflict disrupts HIV care by damaging health infrastructure, displacing populations, interrupting supply chains, and increasing HIV transmission risks. This study examines structural barriers to HIV service delivery in conflict-affected settings and explores adaptive strategies to sustain care. A narrative review approach was used to provide evidence on innovative treatment and prevention models, mental health integration, and policy responses. Key findings show that governance collapse, ART stockouts, workforce shortages, and disrupted data systems undermine HIV care continuity. However, differentiated service delivery, mobile clinics, long-acting injectable ART, community-based models, digital tools, and trauma-informed approaches have shown effectiveness in fragile environments. Integrating mental health into HIV programs addresses the syndemic burden of conflict-related trauma and poor treatment outcomes. Strengthening health systems’ resilience, improving donor coordination, and aligning humanitarian and HIV strategies are essential to ensuring uninterrupted care. Delivering HIV services in conflict zones requires flexible, context-specific, and rights-based approaches. A coordinated, multisectoral response is critical to close equity gaps and advance global HIV goals.

## Full-text entities

- **Diseases:** HIV (MESH:D015658), trauma (MESH:D014947)
- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12947478/full.md

## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12947478/full.md

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Source: https://tomesphere.com/paper/PMC12947478