# Beyond greenness: multidimensional urban nature profiles and arteriosclerotic cardiovascular risk

**Authors:** Pablo Knobel, Aditi Singhvi, Helena Krasnov, Elena Colicino, Itai Kloog, Rachel Litke, Kevin Lane, Alex Federman, Charles Mobbs, Maayan Yitshak Sade

PMC · DOI: 10.1016/j.envint.2025.110033 · Environment international · 2026-02-27

## TL;DR

This study explores how different types of urban nature affect cardiovascular disease risk in New York City residents over 55 years old.

## Contribution

The study introduces a multidimensional classification of urban nature using high-resolution indicators to assess cardiovascular health outcomes.

## Key findings

- Compared to low green areas, waterfront and park access profiles showed reduced cardiovascular disease risk.
- The protective effect of park access was stronger for males, and street trees were more beneficial in areas with more non-Hispanic Black residents.
- Multidimensional urban nature metrics can help promote cardiovascular health equity in cities.

## Abstract

Urban nature, including green and blue spaces, vegetation cover, and biodiversity, has been linked to improved cardiometabolic health. However, most exposure metrics oversimplify complex environmental conditions, limiting their relevance for public health and equity. We developed a multidimensional classification of urban nature using eight high-resolution indicators within 300-meter residential buffers for 36,830 New York City residents aged ≥ 55 years. Using k-means clustering, we identified five distinct exposure profiles based on their mean feature: Low Green, Street Trees, High Cover, Park Access, and Waterfront. We estimated associations between these profiles and incident atherosclerotic cardiovascular disease (ASCVD) from 2013 to 2022 using Cox proportional hazards models with competing risks, and evaluated effect modification by sex, race/ethnicity, and neighborhood-level poverty and racial composition. Over a median follow-up of 3.8 years, 28.7 % of participants experienced an ASCVD event. Compared with the Low-green profile, ASCVD risk was lower for Waterfront (HR = 0.88; 95 % CI: 0.81–0.95), Park Access (0.89; 0.84–0.94), Street Trees (0.92; 0.87–0.98), and High Cover (0.95; 0.88–1.02) profiles in fully adjusted Cox models. Significant interaction term indicated that the association between the Park Access profile and ASCVD risk differed by sex, with stronger protective associations observed for males (interaction p-value: 0.04). Similarly, Street Trees were more protective in areas with higher percentages of non-Hispanic Black residents (interaction p-value: 0.02). These results underscore the value of multidimensional urban nature metrics for understanding and promoting cardiovascular health equity in dense cities.

## Linked entities

- **Diseases:** atherosclerotic cardiovascular disease (MONDO:1060134), cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** ASCVD (MESH:D050197), arteriosclerotic (MESH:D015140)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12947129/full.md

## References

51 references — full list in the complete paper: https://tomesphere.com/paper/PMC12947129/full.md

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Source: https://tomesphere.com/paper/PMC12947129