# Tropheryma whipplei Endocarditis Diagnosed by Tissue 16S rRNA Gene Sequencing: A Case Report

**Authors:** Takashi Maeda, Shun Kohsaka, Nozomi Niimi, Shunsuke Uno, Yoshifumi Uwamino, Mika Nagata, Yasuyuki Shiraishi, Yoshikazu Kishino, Masaki Ieda

PMC · DOI: 10.1016/j.cjco.2025.10.008 · CJC Open · 2025-10-25

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** systole (MESH:D000092244), infectious disease (MESH:D003141), aortic regurgitation (MESH:D001022), embolism (MESH:D004617), BCNE (MESH:D004696), weight loss (MESH:D015431), arthralgia (MESH:D018771), diastolic murmur (MESH:D006337), leukocytosis (MESH:D007964), infected (MESH:D007239), cardiovascular disease (MESH:D002318), T. whipplei (MESH:D001260), malabsorption (MESH:D008286), neutrophilia (MESH:C563010), aortic and mitral regurgitation (MESH:D008944), premature ventricular contractions (MESH:D018879), fever (MESH:D005334), respiratory distress (MESH:D012128), diarrhea (MESH:D003967), Whipple's disease (MESH:D008061), malignancy (MESH:D009369), valve regurgitation (MESH:D006349), pain (MESH:D010146), gout (MESH:D006073), gastrointestinal symptoms (MESH:D012817), inflammation (MESH:D007249), fibrosis (MESH:D005355)
- **Chemicals:** TMP-SMX (MESH:D015662), cefazolin (MESH:D002437), 18F-fluorodeoxyglucose (MESH:D019788), ceftriaxone (MESH:D002443), doxycycline (MESH:D004318)
- **Species:** Bartonella (genus) [taxon 773], Coxiella (genus) [taxon 1260513], Homo sapiens (human, species) [taxon 9606], Felis catus (cat, species) [taxon 9685], Tropheryma whipplei (species) [taxon 2039], Haemophilus (genus) [taxon 724], Cardiobacterium (genus) [taxon 2717]

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## References

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Source: https://tomesphere.com/paper/PMC12946792