# Nanoparticles based interventions for metal(loid) stress mitigation in plants

**Authors:** Anuj Sharma, Vaibhav Sharma, Mahipal Singh Sankhla, Kumud Kant Awasthi, Anjali Awasthi, Garima Awasthi

PMC · DOI: 10.1007/s44154-024-00194-6 · Stress Biology · 2026-02-26

## TL;DR

This review explores how nanoparticles can help plants tolerate metal stress, improving growth and reducing toxicity effects.

## Contribution

The paper systematically reviews the use of nanoparticles to mitigate metal(loid) stress in plants, highlighting their effectiveness in promoting growth and reducing oxidative damage.

## Key findings

- Metal(loid) stress disrupts plant physiology and growth.
- Nanoparticles can enhance antioxidant enzyme activity and reduce oxidative stress in plants.
- Nanoparticle-based interventions show promise in improving plant tolerance to metal(loid) stress.

## Abstract

Metal(loid) stress is one of the key constraints limiting plant growth and productivity, thus threatening agricultural yields and ecosystem health. This review elaborates on the mechanisms through which metal(loid) stress acts on plants, with a special focus on disturbances to key physiological and biochemical aspects. Drawing on global research findings, the review then systematically discusses the interactions between various metal(loid)s and plant components, clarifying the specifity of stress responses across different plant-metal(loid) systems. A central focus of this review is the application of nanoparticles (NPs) as a mitigation strategy to enhance plant growth and improve tolerance to metal(loid) stress. Specifically, it summarizes the multifaceted roles of NPs in this context: promoting plant growth and development, inducing the activity of antioxidant enzymes, and mitigating oxidative stress. This review confirms that metal(loid) stress can strongly inhibit plant growth and physiological functions, but such adverse effects can be significantly alleviated by NPs-based interventions ultimately facilitating the cultivation of more robust and healthy plants. These findings highlight the potential of NPs-mediated strategies as a practical and effective approach to counteract metal(loid) toxicity in plants, providing valuable insights for the development of sustainable agricultural system.

## Full-text entities

- **Genes:** catalase [NCBI Gene 543990]
- **Diseases:** metal (MESH:D013651), Toxic (MESH:D064420), As (MESH:D020261)
- **Chemicals:** Cr (VI) (MESH:C074702), oxygen (MESH:D010100), metalloid (MESH:D058955), Zn (MESH:D015032), salt (MESH:D012492), Pb(NO3)2 (MESH:C017461), gold (MESH:D006046), 24-epibrassinolide (MESH:C023623), singlet oxygen (MESH:D026082), Metal (MESH:D008670), carbon (MESH:D002244), chlorophyll (MESH:D002734), Ni (MESH:D009532), graphene oxide (MESH:C000628730), Pb(CH3COO)2 (MESH:C008261), FeO (MESH:C034236), carotenoid (MESH:D002338), CuCl2 (MESH:C029892), H2O (MESH:D014867), Antimony (MESH:D000965), Zinc Oxide (MESH:D015034), HgCl2 (MESH:D008627), hydroxyl radical (MESH:D017665), Cu (MESH:D003300), Fe2O3 (MESH:C000499), Hg (MESH:D008628), sulfur (MESH:D013455), melatonin (MESH:D008550), Al (MESH:D000535), Si (MESH:D012825), As(III) (-), Superoxide radical (MESH:D013481), H2O2 (MESH:D006861), graphene (MESH:D006108), Se (MESH:D012643), MDA (MESH:D008315), Chromium (MESH:D002857), sulfhydryl (MESH:D013438), OH (MESH:C031356), MgO- (MESH:D008277), lipid (MESH:D008055), TiO2 (MESH:C009495), phytochelatins (MESH:D054811), HM (MESH:D019216), ROS (MESH:D017382), Mn (MESH:D008345), Cadmium (MESH:D002104), Arsenic (MESH:D001151), IAA (MESH:C030737), Pb (MESH:D007854)
- **Species:** Glycine max (soybean, species) [taxon 3847], Pleioblastus variegatus (species) [taxon 591226], Thuidium delicatulum (species) [taxon 94606], Vigna radiata (mung bean, species) [taxon 157791], Ptychanthus striatus (species) [taxon 203655], Phaseolus vulgaris (common bean, species) [taxon 3885], Enterobacter sp. (species) [taxon 42895], Brassica napus (oilseed rape, species) [taxon 3708], Powellomyces sp. EA (species) [taxon 252690], Solanum lycopersicum (tomato, species) [taxon 4081], Homo sapiens (human, species) [taxon 9606], Oryza sativa (Asian cultivated rice, species) [taxon 4530], Cyrto-hypnum sparsifolium (species) [taxon 1547330], Triticum aestivum (bread wheat, species) [taxon 4565], Hordeum vulgare (barley, species) [taxon 4513], Lathyrus oleraceus (garden pea, species) [taxon 3888], Leucaena leucocephala (cassie, species) [taxon 3866]

## Full text

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## Figures

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Source: https://tomesphere.com/paper/PMC12946573