# On the prenatal origins of the myeloproliferative neoplasms

**Authors:** Stephen E. Langabeer

PMC · DOI: 10.17179/excli2025-9181 · EXCLI Journal · 2026-01-13

## Full-text entities

- **Genes:** JAK2 (Janus kinase 2) [NCBI Gene 3717] {aka JTK10}, CALR (calreticulin) [NCBI Gene 811] {aka CALR1, CRT, HEL-S-99n, RO, SSA, cC1qR}, MPL (MPL proto-oncogene, thrombopoietin receptor) [NCBI Gene 4352] {aka C-MPL, CD110, MPLV, THCYT2, THPOR, TPOR}
- **Diseases:** leukemic transformation (MESH:D002472), Philadelphia chromosome-negative (MESH:D010677), ET (MESH:D013920), MPN (MESH:D009369), PV (MESH:D011087), PMF (MESH:D055728), thrombotic tendency (MESH:C536965), AML (MESH:D015470)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** JAK2 V617F

## Full text

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12946437/full.md

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Source: https://tomesphere.com/paper/PMC12946437