# Fluid-structure dynamics of a vibro-impact capsule robot in multiphase intestinal environments

**Authors:** Zepeng Wang, Jiyuan Tian, Yang Liu, Ana Neves, Shyam Prasad

PMC · DOI: 10.1007/s11071-025-12175-z · Nonlinear Dynamics · 2026-02-26

## TL;DR

This paper studies how a capsule robot moves through the intestines, considering the effects of different fluids and how to improve its motion.

## Contribution

The study introduces a validated fluid-structure interaction model for vibro-impact capsule robots in multiphase intestinal environments.

## Key findings

- Higher liquid volume fractions increase resistance to capsule motion due to fluid accumulation and vortex formation.
- Capsule performance improves with higher excitation frequencies and duty cycles, enhancing propulsion and robustness.
- The model was validated against experimental measurements under controlled conditions.

## Abstract

The gastrointestinal tract contains complex fluids, such as mucus, chyme, and water, that can significantly influence capsule robot locomotion by reducing friction or introducing hydrodynamic drag. This study presents a bidirectional fluid-structure interaction model that captures the dynamics of a vibro-impact capsule self-propelling through a fluid-filled small intestine. The model couples the motion of the magnetically actuated capsule, the viscoelastic deformation of the intestinal wall, and a gas-liquid two-phase flow field. Numerical predictions were systematically validated against experimental measurements under controlled laboratory conditions. The results show that an increased liquid volume fraction generates stronger resistance to capsule motion, more so than fluid viscosity alone, by causing fluid accumulation and vortex formation, thereby elevating hydrodynamic pressure and drag. Moreover, capsule performance is improved with higher excitation frequencies and duty cycles, enhancing both propulsion and motion robustness. This work provides a validated numerical platform for designing and optimising magnetically driven capsule robots, advancing their potential for diagnostic and therapeutic applications in the gastrointestinal tract.

## Full-text entities

- **Diseases:** gastrointestinal (GI) diseases (MESH:D005767), infection (MESH:D007239), inflammatory bowel disease (MESH:D015212), cancer (MESH:D009369), intestinal cancers (MESH:D007414), trauma (MESH:D014947)
- **Chemicals:** NdFeB (-), nitrogen (MESH:D009584), polyethylene glycol (MESH:D011092), oxygen (MESH:D010100), polyethylene (MESH:D020959), luminal (MESH:D010634), water (MESH:D014867)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12945900/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12945900/full.md

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Source: https://tomesphere.com/paper/PMC12945900