# Editorial: HLA-G in health and disease: comprehensive insights and future therapeutic directions

**Authors:** Jules Russick, Roberta Rizzo, Ashwin Ajith

PMC · DOI: 10.3389/fimmu.2026.1786277 · Frontiers in Immunology · 2026-02-13

## Full-text entities

- **Genes:** LILRB1 (leukocyte immunoglobulin like receptor B1) [NCBI Gene 10859] {aka CD85J, ILT-2, ILT2, LIR-1, LIR1, MIR-7}, HLA-G (major histocompatibility complex, class I, G) [NCBI Gene 3135] {aka MHC-G}, CD274 (CD274 molecule) [NCBI Gene 29126] {aka ADMIO5, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1}, SPATA2 (spermatogenesis associated 2) [NCBI Gene 9825] {aka PD1, PPP1R145, tamo}
- **Diseases:** primary biliary cholangitis (MESH:D008105), infection (MESH:D007239), colorectal cancer (MESH:D015179), cancer (MESH:D009369), multiple myeloma (MESH:D009101), autoimmune liver inflammation (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12945836