# HPV Vaccination Knowledge and Awareness Among Male University Students in Malaysia: A Cross-Sectional Study

**Authors:** Siqi Li, Fatimah Ahmad Fauzi, Zhihai Jin, Rosliza Abdul Manaf

PMC · DOI: 10.3390/vaccines14020126 · Vaccines · 2026-01-27

## TL;DR

This study finds that male university students in Malaysia have mixed awareness of HPV vaccination, with religion, relationship status, and knowledge being key factors.

## Contribution

The study identifies specific sociodemographic factors influencing HPV vaccination awareness among male university students in Malaysia.

## Key findings

- Non-Muslim students were more likely to have good HPV vaccination awareness compared to Muslim students.
- Students in relationships or married were more aware of HPV vaccination than single students.
- Good HPV-related knowledge was the strongest predictor of vaccination awareness.

## Abstract

Background/Objectives: Human papillomavirus (HPV) vaccines are effective in preventing HPV infection and HPV-related cancers in both males and females. As sexual behavior plays a central role in HPV transmission, male vaccination is important not only for reducing HPV-associated diseases among men but also for limiting viral transmission at the population level. Methods: A cross-sectional study was conducted among male university students in Selangor, Malaysia. Data were collected using a structured questionnaire assessing sociodemographic characteristics, history of sexual intercourse, HPV-related knowledge, and awareness of HPV vaccination. Multivariable logistic regression analysis was performed to identify factors associated with HPV vaccination awareness. Results: Overall, 43.4% of the respondents demonstrated good awareness of HPV vaccination. Multivariable logistic regression analysis identified several factors significantly associated with awareness. Non-Muslim students were more likely to report good awareness of HPV vaccination than Muslim students (AOR = 2.724, 95% CI: 1.150–6.454, p < 0.001). Students who were in a relationship or married demonstrated higher awareness compared with single students (AOR = 3.830, 95% CI: 2.071–7.082, p < 0.001). HPV-related knowledge showed the strongest association, with participants possessing good knowledge being more likely to be aware of HPV vaccination (AOR = 7.012, 95% CI: 4.077–12.059, p < 0.001). In contrast, history of sexual intercourse was not significantly associated with HPV vaccination awareness after adjustment (p = 0.097). Conclusions: Awareness of HPV vaccination among male university students was influenced by religion, relationship status, and HPV-related knowledge. These findings highlight the need for targeted, male-inclusive vaccination education strategies that address sociodemographic differences. University-based interventions may play an important role in improving awareness and increasing HPV vaccine uptake in this population.

## Full-text entities

- **Diseases:** HPV infection (MESH:D030361), cervical cancer (MESH:D002583), injury to (MESH:D014947), cervical, anal, penile, and oropharyngeal malignancies (MESH:D009959), infection (MESH:D007239), sexually transmitted infection (MESH:D012749), sexually (MESH:D050035), cancer (MESH:D009369)
- **Species:** Human papillomavirus (species) [taxon 10566], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12944859/full.md

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Source: https://tomesphere.com/paper/PMC12944859