# Expression of Concern: Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Neoangiogenesis via VEGF/VEGFR-2 Signaling Pathway

PMC · DOI: 10.1371/journal.pone.0343779 · PLOS One · 2026-02-26

## Full-text entities

- **Genes:** VEGFA (vascular endothelial growth factor A) [NCBI Gene 7422] {aka L-VEGF, MVCD1, VEGF, VPF}, Mmp2 (matrix metallopeptidase 2) [NCBI Gene 17390] {aka Clg4a, GelA, MMP-2}, Vegfa (vascular endothelial growth factor A) [NCBI Gene 22339] {aka L-VEGF, Vegf, Vpf}, Kdr (kinase insert domain protein receptor) [NCBI Gene 16542] {aka 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2}, KDR (kinase insert domain receptor) [NCBI Gene 3791] {aka CD309, FLK1, VEGFR, VEGFR2}, Pecam1 (platelet/endothelial cell adhesion molecule 1) [NCBI Gene 18613] {aka Cd31, PECAM-1, Pecam}
- **Diseases:** convulsion (MESH:D012640), paralysis (MESH:D010243), dyspnea (MESH:D004417), tumor (MESH:D009369), overdose (MESH:D062787), coma (MESH:D003128), Breast Cancer (MESH:D001943), toxicity (MESH:D064420), tremor (MESH:D014202)
- **Chemicals:** Isoliquiritigenin (MESH:C040920), xylazine (MESH:D014991), ketamine (-)
- **Species:** Mus musculus (house mouse, species) [taxon 10090]
- **Cell lines:** MDA-MB-231 — Homo sapiens (Human), Breast adenocarcinoma, Cancer cell line (CVCL_0062)

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12944767/full.md

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Source: https://tomesphere.com/paper/PMC12944767