A Symmetric U-Shaped Gate Tunnel FET-ISFET Hybrid Label-Free Biosensor for Highly Sensitive DNA Detection
Yourui An, Yang Li, Shupeng Chen, Shulong Wang, Zhenhao Wen, Xiaoli Yang, Hongxia Liu

TL;DR
This paper introduces a new biosensor combining ISFET and TFET technologies for highly sensitive DNA detection.
Contribution
The novel hybrid biosensor design achieves high current and threshold voltage sensitivity through a symmetric U-shaped gate structure.
Findings
The biosensor achieves a maximum current sensitivity of 99.99% and threshold voltage sensitivity of 124%.
Geometric dimensions and gate dielectric materials significantly impact device performance.
Abstract
Ion-Sensitive Field-Effect Transistors (ISFETs) have been extensively used to detect various biomolecules, as the intrinsic charge of these molecules can change the transistor’s current or threshold voltage. Recently, realizing ISFET biosensors with better performance has attracted much attention. This paper proposes a novel ISFET biosensor by using the advantage of Tunnel Field-Effect Transistor (TFET). The device characteristics and sensing performance are systematically investigated by Silvaco Atlas TCAD simulations. Due to the novel structural design, the proposed sensor achieves a maximum current sensitivity (SIDSmax) of 99.99% and a threshold voltage sensitivity (SVTH) of 124%. To provide optimization guidelines, this work further explored the effect of geometric dimensions and gate dielectric materials on device performance. The excellent performance of the proposed biosensor…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsAdvancements in Semiconductor Devices and Circuit Design · Analytical Chemistry and Sensors · Nanowire Synthesis and Applications
