# Cedarwood Oils: The Wood Essential Oil Compositions from Trees Known as “Cedar”

**Authors:** William N. Setzer, Prabodh Satyal

PMC · DOI: 10.3390/plants15040659 · 2026-02-21

## TL;DR

This paper summarizes the chemical compositions of cedarwood oils from various tree species known as 'cedar', highlighting their use in fragrance and medicine.

## Contribution

The study provides a comprehensive overview of the chemical profiles of cedarwood oils from multiple genera, comparing them with commercial samples.

## Key findings

- Cedrus wood oils are dominated by himachalenes and atlantones.
- Sesquiterpenoids like cedrol and thujopsene are abundant in Cupressus and Juniperus species.
- Monoterpenoids are dominant in Calocedrus species, contributing to their fragrance.

## Abstract

In addition to the true cedars (Cedrus species), there are several genera of trees commonly called “cedar”, including species of Callitropsis, Calocedrus, Cedrela, Chamaecyparis, Cryptomeria, Cupressus, Juniperus, Thuja, and Widdringtonia. The wood essential oils (cedarwood oils) of these trees have been used as flavor and fragrance materials, as well as in medicinal applications. In this study, we present summaries of the wood essential oils from trees known as “cedar”. A literature search was carried out on cedarwood oils and, when available, compared with commercial wood essential oils from the Aromatic Plant Research Center (APRC) collection. Cedrus wood oils are generally dominated by the himachalenes and atlantones. Sesquiterpenoids are abundant in other cedarwood oils, including cedrenes, cedrol, and thujopsene in Cupressus funebris, Juniperus ashei, and Juniperus virginiana. Cadinane sesquiterpenoids are generally abundant in Cedrela odorata and Cryptomeria japonica, while nootkatane sesquiterpenoids are found in Callitropsis nootkatensis and eudesmane sesquiterpenoids are found in Thuja occidentalis. Sesquiterpenoids are generally responsible for the woody fragrances of cedarwood oils, but monoterpenoids can also be dominant (e.g., Calocedrus species).

## Linked entities

- **Chemicals:** cedrol (PubChem CID 65575), thujopsene (PubChem CID 442402)
- **Species:** Cedrus (taxon 3321), Callitropsis nootkatensis (taxon 85954), Calocedrus (taxon 13386), Cedrela odorata (taxon 124947), Cryptomeria japonica (taxon 3369), Juniperus ashei (taxon 13101), Juniperus virginiana (taxon 39584), Thuja occidentalis (taxon 3317)

## Full-text entities

- **Diseases:** anxiety (MESH:D001007), cerebral ischemia (MESH:D002545), inflammatory (MESH:D007249), injury to (MESH:D014947), melanoma (MESH:D008545), obesity (MESH:D009765), colorectal carcinoma (MESH:D015179), cognitive impairment (MESH:D003072), breast adenocarcinoma (MESH:D001943)
- **Chemicals:** Cedrol (MESH:C078669), nootkatone (MESH:C050302), alpha-terpineol (MESH:C016775), hinokitiol (MESH:C009479), delta-cadinene (MESH:C000607799), dichloromethane (MESH:D008752), himachalol (MESH:C010185), alpha-cedrene (MESH:C000393), cadinane (MESH:C508039), terpinen-4-ol (MESH:C034019), thymol (MESH:D013943), Widdrol (MESH:C078670), cubebol (MESH:C442120), nootkatol (MESH:C041991), beta-himachalene (MESH:C412292), Essential oils (MESH:D009822), (E) (MESH:D004540), Cedarwood Oils (MESH:C042023), plicatic acid (MESH:C008938), monoterpenes (MESH:D039821), Oil (MESH:D009821), cuparene (MESH:C483527), East Indian sandalwood oil (MESH:C076763), silica (MESH:D012822), linalool (MESH:C018584), thymoquinone (MESH:C003466), Copaifera epunctata Amshoff (-), ethyl acetate (MESH:C007650), Carvacrol (MESH:C073316), helium (MESH:D006371), thujic acid (MESH:C003462), Pentane (MESH:C033353), 3-thujopsanone (MESH:C000723340), valencene (MESH:C506706), Sesquiterpenoids (MESH:D012717), resin (MESH:D012116), cis-thujopsene (MESH:C433908), CO2 (MESH:D002245)
- **Species:** Cananga odorata (ilang-ilang, species) [taxon 13393], Aniba rosaeodora (species) [taxon 1352902], Widdringtonia nodiflora (species) [taxon 214229], Phytophthora ramorum (sudden oak death agent, species) [taxon 164328], Cedrela odorata (species) [taxon 124947], Pseudomonas aeruginosa (species) [taxon 287], Cedrus brevifolia (species) [taxon 400568], Bacillus subtilis (species) [taxon 1423], Cannula (genus) [taxon 322730], Xenopsylla cheopis (oriental rat flea, species) [taxon 163159], Juniperus (junipers, genus) [taxon 13100], Escherichia coli (E. coli, species) [taxon 562], Radix auricularia (species) [taxon 52793], Thuja plicata (giant arborvitae, species) [taxon 3316], Aedes aegypti (yellow fever mosquito, species) [taxon 7159], Aspergillus fumigatus (species) [taxon 746128], Ixodes scapularis (blacklegged tick, species) [taxon 6945], Trametes versicolor (turkey-tail fungus, species) [taxon 5325], Santalum austrocaledonicum (species) [taxon 293154], Candida albicans (species) [taxon 5476], Ganoderma australe (species) [taxon 34457], Widdringtonia schwarzii (species) [taxon 104009], Human alphaherpesvirus 1 (Herpes simplex virus type 1, no rank) [taxon 10298], Cedrus atlantica (Atlantic cedar, species) [taxon 123597], Cedrus (genus) [taxon 3321], Callitropsis nootkatensis (Alaska yellow cedar, species) [taxon 85954], Eucalyptus globulus (blue gum, species) [taxon 34317], Cryptomeria japonica (Japanese cedar, species) [taxon 3369], Santalum spicatum (species) [taxon 453088], Zingiber officinale (ginger, species) [taxon 94328], Juniperus virginiana (red cedar, species) [taxon 39584], Thuja occidentalis (species) [taxon 3317], Myrrhis odorata (anise, species) [taxon 40880], Callitropsis funebris (species) [taxon 74301], Calocedrus formosana (species) [taxon 54798], Illicium verum (Chinese star-anise, species) [taxon 124778], Cedrus deodara (deodar cedar, species) [taxon 3322], Trichophyton rubrum (species) [taxon 5551], Enterococcus faecalis (species) [taxon 1351], Cedrus libani (Lebanon cedar, species) [taxon 93692], Citrus bergamia (bergamot orange, species) [taxon 380129], Salvia rosmarinus (rosemary, species) [taxon 39367], Rodentia (rodent, order) [taxon 9989], Santalum paniculatum (mountain sandalwood, species) [taxon 453087], Gloeophyllum trabeum (species) [taxon 104355], Melaleuca alternifolia (tea tree, species) [taxon 164405], Homo sapiens (human, species) [taxon 9606], Syzygium aromaticum (clove, species) [taxon 219868], Coptotermes formosanus (Formosan subterranean termite, species) [taxon 36987], Staphylococcus aureus (species) [taxon 1280], Amblyomma americanum (Lone Star tick, species) [taxon 6943], Callosobruchus analis (species) [taxon 380381], C. japonica [taxon 516886], Calocedrus decurrens (incense cedar, species) [taxon 13387], Juniperus procera (African juniper, species) [taxon 62753], Laetiporus sulphureus (chicken-of-the-woods, species) [taxon 5630], Chamaecyparis lawsoniana (Lawson's cypress, species) [taxon 58030], Santalum album (white sandalwood, species) [taxon 35974], Musca domestica (house fly, species) [taxon 7370], Coniophora puteana (species) [taxon 80637]
- **Cell lines:** MDA-MB-231 — Homo sapiens (Human), Breast adenocarcinoma, Cancer cell line (CVCL_0062), HT-29 — Homo sapiens (Human), Colon adenocarcinoma, Cancer cell line (CVCL_0320), A375 — Homo sapiens (Human), Amelanotic melanoma, Cancer cell line (CVCL_0132)

## Figures

14 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12944130/full.md

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Source: https://tomesphere.com/paper/PMC12944130