A Microfluidic Platform for Viscosity Testing of Non-Newtonian Fluids in Engineering and Biomedical Applications
Yii-Nuoh Chang, Da-Jeng Yao
TL;DR
A new microfluidic platform improves viscosity testing for non-Newtonian fluids, useful in biomedical and industrial applications.
Contribution
The platform extends viscosity measurement range and improves accuracy using a flow stabilizer design.
Findings
The platform achieved over 95% viscosity accuracy with low sample volume error.
The N5 design reduced velocity distribution standard deviation by over 50% in simulations.
The chip successfully tracked viscosity changes during milk acidification and gelation.
Abstract
This study presents a microfluidic platform for non-Newtonian fluid viscosity sensing, integrating a high-flow-rate flow field stabilizer to mitigate flow uniformity limitations under elevated flow rate conditions. Building upon an established dual-phase laminar flow principle that determines relative viscosity via channel occupancy, this research aimed to extend the measurable viscosity range from 1–10 cP to 1–50 cP, which covers viscosity regimes relevant to biomedical fluids, dairy products during gelation, and low-to-moderate viscosity industrial liquids. A flow stabilizer was developed through computational fluid dynamics simulations, optimizing three key design parameters: blocker position, porosity, and the number of outlet paths. The N5 design proved most effective, providing over 50% reduction in standard deviation for asymmetric velocity distribution in high-flow simulations.…
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Taxonomy
TopicsBlood properties and coagulation · 3D Printing in Biomedical Research · Rheology and Fluid Dynamics Studies